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Development of ionic-complex-based nanostructured lipid carriers to improve the pharmacokinetic profiles of breviscapine

机译：开发基于离子复合物的纳米结构脂质载体以改善灯盏花素的药代动力学

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摘要

Aim:Breviscapine isolated from the Chinese herb Erigeron breviscapus (Vant) Hand-Mazz is widely used to treat cardiovascular and cerebrovascular diseases. The aim of this study was to improve the pharmacokinetic profiles of breviscapine using nanostructured lipid carrier based on an ionic complex formation.

机译：目的：从中草药灯盏花灯（Erigeron breviscapus（Vant）Hand-Mazz）中分离出的布列卡西汀被广泛用于治疗心血管和脑血管疾病。这项研究的目的是使用基于离子复合物形成的纳米结构脂质载体来改善灯盏花素的药代动力学。

著录项

期刊名称 Acta Pharmacologica Sinica
作者
Mei Li; Yong Zheng; Feng-ying Shan; Jing Zhou; Tao Gong; Zhi-rong Zhang;
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作者单位

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年(卷),期 2013(34),8
年度 2013
页码 1108–1115
总页数 8
原文格式 PDF
正文语种
中图分类药学;
关键词
breviscapine octadecylamine ionic complex nanostructured lipid carriers sustained release pharmacokinetics;

机译：灯盏花素;十八烷基胺;离子配合物;纳米结构脂质载体;缓释;药代动力学;

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专利

1. Development of ionic-complex-based nanostructured lipid carriers to improve the pharmacokinetic profiles of breviscapine [J] . Mei LI, Yong ZHENG, Feng-ying SHAN, 中国药理学报：英文版 . 2013,第008期

机译：基于离子复合物的纳米结构脂质载体的开发，以改善灯盏花素的药代动力学
2. Formulation development of lipid nanoparticles: Improved lipid screening and development of tacrolimus loaded nanostructured lipid carriers (NLC) [J] . Kovacevic Andelka B., Mueller Rainer H., Keck Cornelia M. International Journal of Pharmaceutics . 2020,第期

机译：脂质纳米颗粒的配方发育：改善脂质筛选和巨晕纳米结构脂质载体（NLC）的发育
3. Improved pharmacokinetics and antihyperlipidemic efficacy of rosuvastatin-loaded nanostructured lipid carriers [J] . Rizwanullah Md., Amin Saima, Ahmad Javed Journal of drug targeting . 2017,第1a10期

机译：提高罗苏伐他汀纳米结构脂质载体的药代动力学和抗高兴血血病疗效
4. Improving the Toxicity Profile and Pharmacokinetics of Vasoactive Intestinal Peptide with the PGC Hydrophobic Core Carrier [C] . S. Reichstetter, L. Reed, M. VanBrunt, Annual meeting exposition of the Controlled Release Society . 2010

机译：利用PGC疏水核心载体改善血管活性肠肽的毒性谱和药代动力学
5. The Effect of Artichoke Leaf Extract (Cyanara scolymus L.) on the Pharmacokinetic Profile of Rosuvastatin in Rats Plasma and Their Lipid Lowering Effect by Using HPLC and a Fully Automated Chemistry Analyzer (Snibe? Bioassay 240 Plus) [D] . Al Masalmeh, Ahmad Moussa. 2021

机译：朝鲜蓟叶萃取物（Cyanara scolymus L.）对大鼠血浆中罗苏伐他汀药代动力学谱的影响及其使用HPLC和全自动化学分析仪（SNIBE？Bioassay 240加）
6. Nanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats [O] . Cong Zhang, Fan Peng, Wei Liu, 2014

机译：纳米结构脂质载体作为雷公藤甲素的新型口服递送系统：诱导的药代动力学变化与雄性大鼠毒性降低相关
7. Nanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats [O] . Christopher Wai Kei Lam, Cong Zhang, Fan Peng, 2014

机译：纳米结构脂质载体作为胎冬叶酸的新型口服递送系统：诱导与雄性大鼠毒性降低相关的药代动力学谱的变化

Development of ionic-complex-based nanostructured lipid carriers to improve the pharmacokinetic profiles of breviscapine

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