The Serine Protease Inhibitor 4-(2-aminoethyl) Benzene Sulfonyl Fluoride Hydrochloride Reduces Allergic Inflammation in a House Dust Mite Allergic Rhinitis Mouse Model

摘要

PurposeSerine protease inhibitors are involved in immune development, anti-inflammatory mechanisms, and tissue repair. In the present study, the serine protease inhibitor 4-(2-aminoethyl) benzene sulfonyl fluoride hydrochloride (AEBSF) was evaluated for its prophylactic and therapeutic applications in a mouse model of allergic rhinitis (AR).