The cost-effectiveness of subcutaneous heparin (20,000 iu, twice daily, prefilled syringes), a continuous intravenous infusion of 24,000 iu heparin in 24 h, and the intravenous infusion of 48,000 iu heparin as two consecutive 12-h infusions of 24,000 iu, were compared. The costs were calculated by timing and observing staff in three hospitals, and by noting the costs of what they used. Cannulation of a vein by a doctor took a mean of 4 min 16 s and cost 2.61 pounds. To prepare and administer the 24,000 iu of heparin in a 24-h infusion took a mean of 22 min 42 s/day and cost 9.52 pounds. If a 48,000 iu in 24-h infusion was used it took a mean of 36 min 3 s/day and cost 16.81 pounds. The use of heparin syringes, 20,000 iu subcutaneously twice daily, took 2 min 53 s/day and cost 4.80 pounds. A generic cost formula was calculated to allow for variation in staff or drug costs. The subcutaneous and intravenous routes were assumed to be equally effective on the basis of the medical literature. This study shows that subcutaneous heparin therapy is significantly more cost-effective than intravenous heparin therapy. The reduction in cost and liberation of nursing time mean that the subcutaneous route should be preferred.
展开▼
机译:皮下肝素(20,000 iu,每天两次,预装注射器),在24小时内连续静脉输注24,000 iu肝素以及连续2小时连续2 h输注24,000 iu静脉输注48,000 iu肝素的成本效益。比较。费用是通过对三所医院的工作人员进行时间安排和观察以及他们使用的费用来计算的。医生给静脉插管的平均时间为4分16 s,花费2.61磅。要在24小时内输注24,000 iu肝素并进行管理,平均需要42分钟/ s,每天42 s /天,花费9.52磅。如果在24小时内使用48,000 iu输液,则平均需时36分钟3 s /天,费用为16.81磅。每天两次皮下注射20,000 iu肝素注射器,耗时2分53 s /天,耗资4.80磅。计算出通用成本公式,以考虑人员或药品成本的变化。根据医学文献,皮下和静脉内途径被认为是同样有效的。这项研究表明,皮下肝素治疗比静脉内肝素治疗更具成本效益。成本的降低和护理时间的解放意味着应该首选皮下途径。
展开▼