AB078. Application of array comparative genomic hybridization in clinical diagnostics of intellectual disability/developmental delay in children

摘要

BackgroundArray-based comparative genomic hybridization (array-CGH) has been shown to be a new successful tool in identifying genetic defects underlying intellectual disability (ID) and/or developmental delay (DD). This study was designed to analyze and evaluate the potential pathogenic genomic imbalance in children with unexplained ID/DD and its association with phenotypes, and to investigate the value of array-CGH.