AB030. Study of bone turnover markers and treatment monitoring in osteogenesis imperfecta

摘要

BackgroundOsteogenesis imperfecta (OI), the most prevalent heritable disorders of bone, results from mutations involving several genes responsible for the synthesis or intracellular processing of type I collagen. Bisphosphonates are potent antiresorptive agents, decreasing the incidence of fractures and pain, while increasing energy levels and bone mineral density.