Clinical significance of pancreatic intraepithelial neoplasia in resectable pancreatic cancer on survivals

机译：胰腺上皮内瘤变对可切除胰腺癌生存率的临床意义

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PurposeNoninvasive precursor lesions for pancreatic adenocarcinoma include pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm, and mucinous cystic neoplasm. PanIN is often found synchronously adjacent to resected pancreatic ductal adenocarcinoma (PDAC) tumors. However, its prognostic significance on outcome after PDAC resection is unknown. The purpose of the current study was to determine if the presence of PanIN has a prognostic or predictive effect on survival after resection for PDAC with curative intent.

机译：目的胰腺癌的非侵入性前体病变包括胰腺上皮内瘤变（PanIN），导管内乳头状粘液性肿瘤和粘液性囊性肿瘤。 PanIN通常与切除的胰管腺癌（PDAC）肿瘤同步发现。但是，其对PDAC切除后预后的预后意义尚不清楚。本研究的目的是确定PanIN的存在是否对具有治愈意图的PDAC切除后的生存具有预后或预测作用。

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期刊名称 Annals of Surgical Treatment and Research
作者
Da-Young Yu; Young-Dong Yu; Wan-Bae Kim; Hyung-Joon Han; Sae-Byul Choi; Dong-Sik Kim; Sang-Yong Choi; Joo-Young Kim; Hyeyoon Chang; Baek-Hui Kim;
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作者单位

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年(卷),期 2018(94),5
年度 2018
页码 247–253
总页数 7
原文格式 PDF
正文语种
中图分类外科学;
关键词
Intraepithelial neoplasm Pancreatic neoplasms Survival;

机译：上皮内肿瘤;胰腺肿瘤;生存;
入库时间 2022-08-17 16:08:27

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专利

1. Absence of pancreatic intraepithelial neoplasia predicts poor survival after resection of pancreatic cancer. [J] . Benjamin G Hassid, Aimee L Lucas, Marcela Salomao, Pancreas . 2014,第7期

机译：胰腺上皮内瘤样病变的缺乏预示着胰腺癌切除后的生存率很低。
2. Expression of neuropeptide Y and its receptors Y1 and Y2 in pancreatic intraepithelial neoplasia and invasive pancreatic cancer in a transgenic mouse model and human samples of pancreatic cancer [J] . Jens Waldmann, Volker Fendrich, Martin Reichert, Journal of Surgical Research: Clinical and Laboratory Investigation . 2018,第期

机译：在转基因小鼠模型和胰腺癌中胰腺上皮内瘤形成和侵袭性胰腺癌中的神经肽Y及其受体Y1和Y2的表达及胰腺癌
3. Metabonomic alterations from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma facilitate the identification of biomarkers in serum for early diagnosis of pancreatic cancer [J] . Xianchao Lin, Bohan Zhan, Shi Wen, Molecular BioSystems . 2016,第9期

机译：从胰腺上皮内瘤变到胰腺导管腺癌的代谢组学改变有助于血清中生物标志物的鉴定，以早期诊断胰腺癌
4. Pancreatic Cancer Survival Prediction Using CT Scans and Clinical Variables [C] . Li Sun, Songtao Zhang Simulation, image processing, and ultrasound systems for assisted diagnosis and navigation . 2018

机译：使用CT扫描和临床变量预测胰腺癌的生存
5. Metabolic Profiling of Urine, Fecal, and Serum Samples and Pancreatic Tumors and Evaluation of HMGA1 Expression Levels in Pancreatic Intraepithelial Neoplasia Cells in the Ptf1a-Cre; LSL-KrasG12D Transgenic Mouse Model of Pancreatic Cancer [D] . Schmahl, Michelle J. 2018

机译：Ptf1a-Cre胰腺上皮内瘤变细胞中尿液，粪便和血清样品和胰腺肿瘤的代谢谱分析和HMGA1表达水平的评估； LSL-KrasG12D胰腺癌转基因小鼠模型
6. Absence of Pancreatic Intraepithelial Neoplasia (PanIN) Predicts Poor Survival Following Resection of Pancreatic Cancer [O] . Benjamin G. Hassid, Aimee L. Lucas, Marcela Salomao, -1

机译：胰腺上皮内瘤样病变（PanIN）的缺乏预示着胰腺癌切除术后的不良生存
7. Table 5.5.a.1 Tumor size and treatment (rate of resectability) Figure 5.5.a.2 Cumulative survival of the patients after pancreatectomy for TS1 cancer according to residual tumors Figure 5.5.a.3 Cumulative survival of the patients with TS1 cancer according to extent of lymph node dissection Figure 5.5.a.4 Combined resection of portal vein and cumulative survival of the patients after pancreatectomy for TS1 cancer of UICC Stage IIa or IIb in the pancreatic head Figure 5.5.a.5 Combined resection of peripancreatic plexus and cumulative survival of the patients after pancreatectomy for TS1 cancer of UICC Stage IIa or IIb in the pancreatic head Figure 5.5.a.6 Combined resection of peripancreatic plexus when there is no plexus infiltration and cumulative survival of the patients after pancreatectomy for TS1 cancer of UICC Stage IIa or IIb in the pancreatic head Figure 5.5.a.7 Combined resection of artery and cumulative survival of the patients after pancreatectomy for TS1 cancer of UICC Stage IIa or IIb in the pancreatic head Figure 5.5.a.8 Combined resection of portal vein and cumulative survival of the patients after pancreatectomy for TS2 (2.1-4.0 cm) cancer of UICC Stage IIa or IIb in the pancreatic head Figure 5.5.a.9 Combined resection of peripancreatic plexus and cumulative survival of the patients after pancreatectomy for TS2 (2.1-4.0 cm) cancer of UICC Stage IIa or IIb in the pancreatic head [O] . 2007

机译：表5.5.a.1肿瘤大小和治疗（重新切性率）图5.5.a.2根据残留肿瘤对TS1癌胰腺切除后患者的累积存活图5.5.A.3累积存活根据淋巴结解剖的程度，TS1癌症的患者图5.5.A.4在胰头胰腺IIA或IIB癌症术后胰岛切除术后的门静脉和累积患者的累积存活图5.5。 A.5在胰头术后IIA或IIB胰腺切除术后，患者胰腺癌丛和患者累积存活的组合图5.5.A.6当没有丛浸润时，围裙丛生的围嘴巴丛的切除胰腺切除术后胰腺切除术后胰腺炎癌症的累积存活图5.5.A.7在TS1癌症胰腺切除后患者的动脉和累积存活的组合UICC阶段IIA或IIB在胰头图5.5.A.8在胰头胰腺阶段IIA或IIB癌症的胰腺切除后，患者的门静脉和累积患者的累积存活率图5.5.A.9在胰头胰腺阶段IIA或IIB的胰腺切除术后胰腺切除术后患者患者患者患者的累积生存的组合和胰腺头

Clinical significance of pancreatic intraepithelial neoplasia in resectable pancreatic cancer on survivals

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