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In Vivo Efficacy of Meropenem with a Novel Non-β-Lactam–β-Lactamase Inhibitor Nacubactam against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model

机译：美罗培南与新型非β-内酰胺-β-内酰胺酶抑制剂Nacubactam对革兰阴性生物的体内功效革兰阴性生物在小鼠复杂的尿路感染模型中表现出多种耐药机制

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期刊名称 Antimicrobial Agents and Chemotherapy
作者
Marguerite L. Monogue; Sara Giovagnoli; Caterina Bissantz; Claudia Zampaloni; David P. Nicolau;
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作者单位

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年(卷),期 2018(62),9
年度 2018
页码 e02596-17
总页数 8
原文格式 PDF
正文语种
中图分类药学;微生物学;
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1. In Vivo Efficacy of Meropenem with a Novel Non-beta-Lactam-beta-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model [J] . Monogue Marguerite L., Giovagnoli Sara, Bissantz Caterina, Antimicrobial agents and chemotherapy. . 2018,第9期

机译：梅洛涅姆与新型非β-内酰胺β-内酰胺酶抑制剂，NaCACActam的体内疗效，抗革兰阴性生物，在鼠复杂尿路感染模型中表现出各种抗性机制
2. Efficacy of Human-Simulated Epithelial Lining Fluid Exposure of Meropenem-Nacubactam Combination against Class A Serine beta-Lactamase-Producing Enterobacteriaceae in the Neutropenic Murine Lung Infection Model [J] . Asempa Tomefa E., Motos Ana, Abdelraouf Kamilia, Journal of neurosurgical sciences . 2019,第4期

机译：Usopenem-NaCucActam组合对猪鼠肺部感染模型中丝氨酸β-内酰胺酶肠杆菌植物的疗效对梅洛涅 - Nacubactam组合的疗效
3. Efficacy of Human-Simulated Epithelial Lining Fluid Exposure of Meropenem-Nacubactam Combination against Class A Serine beta-Lactamase-Producing Enterobacteriaceae in the Neutropenic Murine Lung Infection Model [J] . Asempa Tomefa E., Motos Ana, Abdelraouf Kamilia, Antimicrobial agents and chemotherapy. . 2019,第4期

机译：Usopenem-NaCucActam组合对猪鼠肺部感染模型中丝氨酸β-内酰胺酶肠杆菌植物的疗效对梅洛涅 - Nacubactam组合的疗效
4. Antimicrobial resistance and selected beta-lactam resistance genes in Escherichia coli from canine urinary tract infections. [D] . Khashayar, Behrouz. 2010

机译：来自犬尿道感染的大肠杆菌中的抗菌素耐药性和选定的β-内酰胺耐药基因。
5. 1436. Comparison of Ceftazidime–Avibactam Ceftolozane–Tazobactam Piperacillin–Tazobactam and Meropenem Activities When Tested Against Gram-Negative Organisms Isolated From Complicated Urinary Tract Infections [O] . Helio S Sader, Robert K Flamm, Mariana Castanheira, -1

机译：1436.头孢他啶-阿维巴坦头孢洛氮烷-他唑巴坦哌拉西林-他唑巴坦和美罗培南活性的比较针对从复杂的尿路感染中分离出来的革兰氏阴性菌进行了测试
6. Humanized Exposures of a β-Lactam/β-Lactamase Inhibitor (BL-BLI), Tazobactam (TZB), Versus a Non-β-Lactam/β-Lactamase Inhibitor, Avibactam (AVI), With or Without Colistin (CST), Against Acinetobacter baumannii (AB) in Murine Thigh and Lung Infection Models [O] . Marguerite Monogue, George Sakoulas, David P. Nicolau 2016

机译：β-内酰胺/β-乳酰胺酶抑制剂（BL-BLI），Tazobactam（TZB）的人源化暴露与非β-内酰胺/β-内酰胺酶抑制剂，Avibactam（AVI），有或没有Colistin（CST），反对在鼠大腿和肺部感染模型中的AcineTobacterBaumannii（AB）

In Vivo Efficacy of Meropenem with a Novel Non-β-Lactam–β-Lactamase Inhibitor Nacubactam against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model

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