Discordant Resistance to Kanamycin and Amikacin in Drug-Resistant Mycobacterium tuberculosis

机译：耐药结核分枝杆菌对卡那霉素和丁胺卡那霉素的耐药性不一致

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It is generally thought that there is full cross-resistance in Mycobacterium tuberculosis between the aminoglycoside drugs kanamycin and amikacin. However, kanamycin resistance and amikacin susceptibility were seen in 43 of 79 (54%) multidrug-resistant Estonian isolates, indicating that there might be a need to test the resistance of M. tuberculosis isolates to both drugs.

机译：通常认为，在结核分枝杆菌中，氨基糖苷类药物卡那霉素和丁胺卡那霉素之间具有完全的交叉耐药性。但是，在79株耐多药的爱沙尼亚分离株中，有43株（占54％）中发现有卡那霉素耐药性和丁胺卡那霉素敏感性，这表明可能需要测试结核分枝杆菌对两种药物的耐药性。

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期刊名称 Antimicrobial Agents and Chemotherapy
作者
Annika Krüüner; Pontus Jureen; Klavdia Levina; Solomon Ghebremichael; Sven Hoffner;
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作者单位

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年(卷),期 2003(47),9
年度 2003
页码 2971–2973
总页数 3
原文格式 PDF
正文语种
中图分类药学;微生物学;
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专利

1. Discordant resistance to kanamycin and amikacin in drug-resistant Mycobacterium tuberculosis. [J] . Kruuner A, Jureen P, Levina K, Antimicrobial agents and chemotherapy. . 2003,第9期

机译：耐药结核分枝杆菌对卡那霉素和丁胺卡那霉素的耐药性不一致。
2. Genotypic Susceptibility Testing of Mycobacterium tuberculosis Isolates for Amikacin and Kanamycin Resistance by Use of a Rapid Sloppy Molecular Beacon-Based Assay Identifies More Cases of Low-Level Drug Resistance than Phenotypic Lowenstein-Jensen Testing [J] . Soumitesh Chakravorty, Jong Seok Lee, Eun Jin Cho, Journal of Clinical Microbiology . 2015,第1期

机译：快速的基于分子信标的结核分枝杆菌分离株对丁胺卡那霉素和卡那霉素抗性的基因型药敏试验比表型Lowenstein-Jensen试验鉴定出更多的低水平抗药性病例
3. Correlation between phenotypic and genotypic drug resistance to kanamycin and amikacin in clinical isolates of Mycobacterium tuberculosis [J] . Azam Ahmadi, Maryam Sadrnia, Mohammad Arjomandzadegan, Iranian Journal of Microbiology . 2020,第5期

机译：结核分枝杆菌临床分离株对卡那霉素和氨基酰磷酸盐素和氨基辛酸的相关性
4. Molecular analysis of kanamycin ressitance of mycobacterium tuberculosis [C] . Hatsumi Taniguchi, Bin Chang 7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai . 2000

机译：结核分枝杆菌卡那霉素抗性的分子分析
5. Low-Level Kanamycin Resistance in Mycobacterium tuberculosis: Molecular Mechanisms and Clinical Implications. [D] . Zaunbrecher, Mary Analise. 2010

机译：卡那霉素在结核分枝杆菌中的低水平耐药性：分子机制和临床意义。
6. Genotypic Susceptibility Testing of Mycobacterium tuberculosis Isolates for Amikacin and Kanamycin Resistance by Use of a Rapid Sloppy Molecular Beacon-Based Assay Identifies More Cases of Low-Level Drug Resistance than Phenotypic Lowenstein-Jensen Testing [O] . Soumitesh Chakravorty, Jong Seok Lee, Eun Jin Cho, 2015

机译：快速的基于分子信标的结核分枝杆菌分离株对丁胺卡那霉素和卡那霉素抗性的基因型药敏试验比表型Lowenstein-Jensen试验鉴定出更多的低水平抗药性病例
7. Discordant Resistance to Kanamycin and Amikacin in Drug-Resistant Mycobacterium tuberculosis [O] . Krüüner, Annika, Jureen, Pontus, Levina, Klavdia, 2003

机译：耐药结核分枝杆菌对卡那霉素和丁胺卡那霉素的耐药性不一致

Discordant Resistance to Kanamycin and Amikacin in Drug-Resistant Mycobacterium tuberculosis

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