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Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs

机译：N-甲基氨基甲硫咪啶对豚鼠生殖器单纯疱疹病毒2型脱落和感染的疗效

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摘要

BackgroundCurrent approved nucleoside therapies for genital herpes simplex virus (HSV) infections are effective but improved therapies are needed for treatment of both acute and recurrent diseases.

机译：背景技术目前批准的用于生殖器单纯疱疹病毒（HSV）感染的核苷疗法是有效的，但需要改进的疗法来治疗急性和复发性疾病。

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期刊名称 Antiviral Chemistry Chemotherapy
作者
David I Bernstein; Fernando J Bravo; Derek A Pullum; Hui Shen; Mei Wang; Aquilur Rahman; Robert I Glazer; Rhonda D Cardin;
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作者单位

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年(卷),期 2015(24),1
年度 2015
页码 19–27
总页数 9
原文格式 PDF
正文语种
中图分类人体病毒学（致病病毒）;病毒（滤过性病毒）;
关键词
Herpes simplex virus genital herpes N-methanocarbathymidine recurrent herpes;

机译：单纯疱疹病毒;生殖器疱疹;N-甲氨基甲蝶啶;复发性疱疹;
入库时间 2022-08-17 16:05:02

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专利

1. Impact of Immunization with Glycoprotein D2/AS04 on Herpes Simplex Virus Type 2 Shedding into the Genital Tract in Guinea Pigs That Become Infected. [J] . Bourne N, Milligan GN, Stanberry LR, The Journal of Infectious Diseases . 2005,第12期

机译：糖蛋白D2 / AS04免疫对被感染的豚鼠2型单纯疱疹病毒脱落到生殖道的影响。
2. Effects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig [J] . Bernstein David I., Earwood Julie D., Bravo Fernando J., Vaccine . 2011,第11期

机译：单纯疱疹病毒2型糖蛋白疫苗和CLDC佐剂对豚鼠生殖器疱疹感染的影响
3. Effect of an immune enhancer, GPI-0100, on vaccination with live attenuated herpes simplex virus (HSV) type 2 or glycoprotein D on genital HSV-2 infections of guinea pigs. [J] . Quenelle DC, Collins DJ, Rice TL, Antiviral Research . 2008,第2期

机译：免疫增强剂GPI-0100对豚鼠生殖器HSV-2感染的2型减毒活单纯疱疹病毒（HSV）或糖蛋白D接种的影响。
4. Dielectric investigations of the membrane properties of baby hamster kidney fibroblasts following infection with Herpes Simplex Virus, type 1 [C] . Archer, S., Rixon, Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE . 1998

机译：1型单纯疱疹病毒感染后婴儿仓鼠肾成纤维细胞膜特性的介电研究
5. Mucosal immune responses in the murine female genital tract against intravaginal infection with herpes simplex virus type-2. [D] . Tang, Vera A. 2010

机译：鼠女性生殖道中针对2型单纯疱疹病毒阴道内感染的粘膜免疫反应。
6. Efficacy of the acyclic nucleoside 9-(13-dihydroxy-2-propoxymethyl)guanine against primary and recrudescent genital herpes simplex virus type 2 infections in guinea pigs. [O] . E B Fraser-Smith, D F Smee, T R Matthews 1983

机译：无环核苷9-（13-二羟基-2-丙氧基甲基）鸟嘌呤对豚鼠原发性和复发性生殖器单纯疱疹病毒2型感染的功效。
7. Efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine against primary and recrudescent genital herpes simplex virus type 2 infections in guinea pigs. [O] . Fraser-Smith, E B, Smee, D F, Matthews, T R 1983

机译：无环核苷9-（1,3-二羟基-2-丙氧基甲基）鸟嘌呤对豚鼠原发性和复发性生殖器单纯疱疹病毒2型感染的功效。

Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs

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