Transformation of Morphine by Resting Cells and Cell-Free Systems of Arthrobacter Sp

摘要

Morphine can be transformed into 14-hydroxymorphine and a related unidentified material by resting cells of an Arthrobacter species. Cell-free extracts containing the transforming enzyme(s) have been obtained. O2, Fe²⁺, and reduced nicotinamide adenine dinucleotide stimulate the transformation.