The Oslo Health Study: A Dietary Index Estimating Frequent Intake of Soft Drinks and Rare Intake of Fruit and Vegetables Is Negatively Associated with Bone Mineral Density

摘要

Background. Since nutritional factors may affect bone mineral density (BMD), we have investigated whether BMD is associated with an index estimating the intake of soft drinks, fruits, and vegetables. Methods. BMD was measured in distal forearm in a subsample of the population-based Oslo Health Study. 2126 subjects had both valid BMD measurements and answered all the questions required for calculating a Dietary Index = the sum of intake estimates of colas and non-cola beverages divided by the sum of intake estimates of fruits and vegetables. We did linear regression analyses to study whether the Dietary Index and the single food items included in the index were associated with BMD.Results. There was a consistentnegative association between the Dietary Indexand forearm BMD. Among the single indexcomponents, colas and non-cola soft drinks werenegatively associated with BMD. The negativeassociation between the Dietary Index and BMDprevailed after adjusting for gender, age, andbody mass index, length of education, smoking,alcohol intake, and physical activity.Conclusion. An index reflectingfrequent intake of soft drinks and rare intakeof fruit and vegetables was inversely related todistal forearm bone mineraldensity.