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Simultaneous Determination of 6-Mercaptopurine and its Oxidative Metabolites in Synthetic Solutions and Human Plasma using Spectrophotometric Multivariate Calibration Methods

机译：分光光度法多元校正法同时测定合成溶液和人体血浆中的6-巯基嘌呤及其氧化代谢产物

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Introduction 6-Mercaptopurine (6MP) is an important chemotherapeutic drug in the conventional treatment of childhood acute lymphoblastic leukemia (ALL). It is catabolized to 6-thiouric acid (6TUA) through 8-hydroxo-6-mercaptopurine (8OH6MP) or 6-thioxanthine (6TX) intermediates.

机译：简介6-巯基嘌呤（6MP）是常规治疗儿童急性淋巴细胞白血病（ALL）的重要化学治疗药物。通过8-羟基-6-巯基嘌呤（8OH6MP）或6-硫代黄嘌呤（6TX）中间体将其分解为6-硫尿酸（6TUA）。

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期刊名称 BioImpacts : BI
作者
Mohammad-Hossein Sorouraddin; Mohammad-Yaser Khani; Kaveh Amini; Abdolhossein Naseri; Davoud Asgari; Mohammad-Reza Rashidi;
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作者单位

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年(卷),期 2011(1),1
年度 2011
页码 53–62
总页数 10
原文格式 PDF
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关键词
6-Mercaptopurine Oxidative Metabolites Multivariate Spectrophotometric;

机译：6-巯基嘌呤;氧化代谢产物;多元;分光光度法;

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专利

1. Simultaneous Determination of 6-Mercaptopurine and its Oxidative Metabolites in Synthetic Solutions and Human Plasma using Spectrophotometric Multivariate Calibration Methods [J] . Sorouraddin M, Khani M, Amini K, BioImpacts . 2011,第1期

机译：分光光度法多元校正法同时测定合成溶液和人体血浆中的6-巯基嘌呤及其氧化代谢产物
2. Simultaneous spectrophotometric determination of phenanthridine, phenanthridinone and phenanthridine N-oxide using multivariate calibration methods [J] . Mohammad-Hossein Sorouraddin, Kaveh Amini, Abdolhossein Naseri Central European Journal of Chemistry . 2010,第1期

机译：多元校正法同时分光光度法测定菲啶，菲啶酮和菲啶N-氧化物
3. Simultaneous spectrophotometric determination of phenanthridine, phenanthridinone and phenanthridine N-oxide using multivariate calibration methods [J] . Mohammad-Hossein Sorouraddin, Kaveh Amini, Abdolhossein Naseri, Open Chemistry . 2010,第1期

机译：多元校正法同时分光光度法测定菲啶，菲啶酮和菲啶N-氧化物
4. A rapid LC/MS/MS method for simultaneous determination of vildagliptin and two metabolites in monkey, human and rat plasma [C] . Wei Zhou, Sagar Kawle, Shaoyong Li, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

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5. Simultaneous spectrophotometric and chemometric determination of cholesterol and mono-/polyunsaturated fatty acids [D] . Dumancas, Gerard G. 2012

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6. Spectrophotometric and Multivariate Calibration Techniques for Simultaneous Determination of Different Drugs in Pharmaceutical Formulations and Human Urine: Evaluation of Greenness Profile [O] . Ahmed Mostafa 2020

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7. Simultaneous Spectrophotometric Determination of Amitriptyline Hydrochloride and Chlordiazepoxide in Pharmaceutical Tablets by Multivariate Calibration Method [O] . Amir H. M. Sarrafi, Ziba Khodakarami, Masoumeh Karkeabadi 2009

机译：多元校准法同时分光光度法药片中药片中的氨基氯酰胺和氯芳基氧化物

Simultaneous Determination of 6-Mercaptopurine and its Oxidative Metabolites in Synthetic Solutions and Human Plasma using Spectrophotometric Multivariate Calibration Methods

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