Identification of fragments from Autographa Californica polyhedrin protein essential for self-aggregation and exogenous protein incorporation

摘要

BackgroundBaculoviruses are widely used for the production of recombinant proteins, biopesticides and as gene delivery systems. One of the viral forms called polyhedra has been recently exploited as a scaffold system to incorporate or encapsulate foreign proteins or peptide fragments. However, an efficient strategy for foreign protein incorporation has not been thoroughly studied.