The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5-nucleotidase

摘要

BackgroundThe purine salvage enzyme inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase catalyzes degradation of IMP to inosine. Although this enzymatic activity has been purified and characterized in Saccharomyces cerevisiae, the gene encoding IMP 5'-nucleotidase had not been identified.