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Intuitive representation of surface properties of biomolecules using BioBlender

机译:使用BioBlender直观表示生物分子的表面特性

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摘要

BackgroundIn living cells, proteins are in continuous motion and interaction with the surrounding medium and/or other proteins and ligands. These interactions are mediated by protein features such as electrostatic and lipophilic potentials. The availability of protein structures enables the study of their surfaces and surface characteristics, based on atomic contribution. Traditionally, these properties are calculated by physico-chemical programs and visualized as range of colors that vary according to the tool used and imposes the necessity of a legend to decrypt it. The use of color to encode both characteristics makes the simultaneous visualization almost impossible, requiring these features to be visualized in different images. In this work, we describe a novel and intuitive code for the simultaneous visualization of these properties.
机译:背景技术在活细胞中,蛋白质持续运动并与周围的培养基和/或其他蛋白质和配体相互作用。这些相互作用是由蛋白质特征介导的,例如静电和亲脂性电位。蛋白质结构的可获得性使得能够基于原子贡献研究其表面和表面特性。传统上,这些属性是通过理化程序计算的,并可视化为颜色范围,颜色范围根据所使用的工具而有所不同,并需要图例对其进行解密。使用颜色来编码两个特征使得几乎不可能同时进行可视化,从而要求这些特征在不同的图像中可视化。在这项工作中,我们描述了同时可视化这些属性的新颖直观的代码。

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