Repair of cartilage defects in osteoarthritis rats with induced pluripotent stem cell derived chondrocytes

摘要

BackgroundThe incapacity of articular cartilage (AC) for self-repair after damage ultimately leads to the development of osteoarthritis. Stem cell-based therapy has been proposed for the treatment of osteoarthritis (OA) and induced pluripotent stem cells (iPSCs) are becoming a promising stem cell source.