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Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice

机译：黄烷酮衍生物庞西林在小鼠急性和慢性炎症性疼痛模型中的抗痛觉过敏特性

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BackgroundPoncirin is flavanone derivative (isolated from Poncirus trifoliata) with known pharmacological activities such as anti-tumor, anti-osteoporotic, anti-inflammatory and anti-colitic. The present study aimed to explore the anti-allodynic and anti-hyperalgesic potentials of poncirin in murine models of inflammatory pain.

机译：背景Poncirin是黄烷酮衍生物（从Poncirus trifoliata分离），具有已知的药理活性，例如抗肿瘤，抗骨质疏松，抗炎和抗结肠炎。本研究旨在探讨poncirin在炎性小鼠模型中的抗痛觉过敏和抗痛觉过敏的潜力。

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期刊名称 BMC Pharmacology Toxicology
作者
Ruqayya Afridi; Ashraf Ullah Khan; Sidra Khalid; Bushra Shal; Hina Rasheed; Muhammad Zia Ullah; Omer Shehzad; Yeong Shik Kim; Salman Khan;
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作者单位

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年(卷),期 2019(20),-1
年度 2019
页码 57
总页数 16
原文格式 PDF
正文语种
中图分类药学;
关键词
Poncirin Inflammatory pain Cytokines Hyperalgesia Allodynia;

机译：poncirin;炎性疼痛;细胞因子;痛觉过敏;异常性疼痛;

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1. Mechanism underlying anti-hyperalgesic and anti-allodynic properties of anomalin in both acute and chronic inflammatory pain models in mice through inhibition of NF-κB, MAPKs and CREB signaling cascades [J] . KhanS., ShehzadO., ChunJ., European Journal of Pharmacology: An International Journal . 2013,第1a3期

机译：通过抑制NF-κB，MAPKS和CREB信号级联小鼠急性和慢性炎症疼痛模型中急性和慢性炎性疼痛模型的异常和抗恶性分解的机制
2. Plant derived alkaloid (-)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models [J] . DaSilvaK.A.B.S., ManjavachiM.N., PaszcukA.F., Neuropharmacology . 2012,第2期

机译：植物来源的生物碱（-）-胱氨酸在急性和慢性炎症和神经性疼痛模型中均具有抗炎和抗痛觉过敏作用
3. Chiral tetrahydroquinoline derivatives as potent anti-hyperalgesic agents in animal models of sustained inflammation and chronic neuropathic pain. [J] . Di-Fabio R, Alvaro G, Bertani B, Bioorganic and Medicinal Chemistry Letters . 2007,第5期

机译：手性四氢喹啉衍生物在持续炎症和慢性神经性疼痛的动物模型中作为有效的抗痛觉过敏药。
4. Bio-MEMS based sensor for acute and chronic pain management: An online measurement strategy for using biomedicai MEMS sensor in the assessment of pain intensity and study of inflammation [C] . Sathiyabama G., Krishnan S. Sankara, Saravanan D., Second IEEE National Conference On Emerging Trends In New amp; Renewable Energy Sources amp; Energy Management . 2014

机译：用于急性和慢性疼痛管理的基于生物MEMS的传感器：使用生物医学MEMS传感器评估疼痛强度和研究炎症的在线测量策略
5. Transition from acute to chronic pain: A biopsychosocial model of chronicity [D] . Young, Corinna W. 2002

机译：从急性疼痛到慢性疼痛的转变：慢性的生物心理社会模型
6. Analgesic and Anti-Inflammatory Effects of Perampanel in Acute and Chronic Pain Models in Mice: Interaction With the Cannabinergic System [O] . Carmen De Caro, Claudia Cristiano, Carmen Avagliano, 2020

机译：小鼠急性和慢性疼痛模型中Perampanel的镇痛和抗炎作用：与大麻能系统的相互作用
7. Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice [O] . Ruqayya Afridi, Ashraf Ullah Khan, Sidra Khalid, 2019

机译：小鼠急性慢性炎性疼痛模型中黄酮衍生卟啉的抗痛觉痛题性质

Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice

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