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A stable CC-chemokine receptor (CCR)-5 tropic virus is correlated with the persistence of HIV RNA at less than 2.5 copies in successfully treated naïve subjects

机译：稳定的CC趋化因子受体（CCR）-5热带病毒与成功治疗过的未治疗个体中HIV RNA的持久性低于2.5拷贝相关

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BackgroundTo determine if tropism for CXCR4 or CCR5 correlates with cellular HIV DNA load, residual viraemia and CD4 count in 219 successfully treated naive subjects with HIV infection enrolled in five infectious diseases units in Northeastern Italy.

机译：背景为了确定CXCR4或CCR5的向性是否与细胞HIV DNA负荷相关，在意大利东北部的五个传染病科中，对219名成功治疗的初次感染HIV的初次受试者进行了残留病毒血症和CD4计数。

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期刊名称 BMC Infectious Diseases
作者
Saverio Giuseppe Parisi; Samantha Andreis; Carlo Mengoli; Renzo Scaggiante; Mario Cruciani; Roberto Ferretto; Vinicio Manfrin; Sandro Panese; Monica Basso; Caterina Boldrin; Stefania Bressan; Loredana Sarmati; Massimo Andreoni; Giorgio Palù;
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年(卷),期 2013(13),-1
年度 2013
页码 314
总页数 8
原文格式 PDF
正文语种
中图分类病毒传染病;
关键词
HIV tropism HIV residual viraemia HIV DNA load;

机译：HIV嗜性;HIV残留病毒血症;HIV DNA载量;

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专利

1. A stable CC-chemokine receptor (CCR)-5 tropic virus is correlated with the persistence of HIV RNA at less than 2.5 copies in successfully treated na?ve subjects [J] . Saverio G Parisi, Samantha Andreis, Carlo Mengoli, BMC Infectious Diseases . 2013,第1期

机译：稳定的CC趋化因子受体（CCR）-5热带病毒与在成功治疗的初次受试者中HIV RNA的持久性低于2.5拷贝相关
2. A recombinant vesicular stomatitis virus encoding CCR5-tropic HIV-1 receptors targets HIV-1-infected cells and controls HIV-1 infection [J] . Okuma Kazu, Fukagawa Koji, Kohma Takuya, Microbes and infection . 2017,第4a5期

机译：编码CCR5-Tropic HIV-1受体的重组腔体口炎病毒靶向HIV-1感染的细胞并对对照HIV-1感染进行治疗
3. Prevalence of R5 strains in multi-treated HIV subjects and impact of new regimens including maraviroc in a selected group of patients with CCR5-tropic HIV-1 infection [J] . Isabella Bon, Alberto Clò, Marco Borderi, International journal of infectious diseases : . 2013,第10期

机译：R5菌株在经过多重治疗的HIV受试者中的患病率以及包括maraviroc在内的新方案对一组CCR5嗜性HIV-1感染患者的影响
4. Predicting the Co-receptors (CCR5 and CXCR4) of the Viruses R5, X4 and R5X4 that Cause AIDS (HIV-1) in Cells CD4 using The Bayes Classifier [C] . Francisco Javier Luna Rosas, Julio Cesar Martinez Romo, Carlos Alejandro de Luna Ortega, International Conference on Bioinformatics and Computational Biology . 2014

机译：预测病毒R5，X4和R5X4的共同受体（CCR5和CXCR4），其使用贝叶斯分类器导致细胞CD4中的艾滋病（HIV-1）
5. Persistence of HIV-1 despite highly active antiretroviral therapy (HAART) and immune responses: Evidence for a novel viral reservoir in patients on HAART and characterization of HIV-1 virus and immune responses in elite suppressors. [D] . Bailey, Justin R. 2007

机译：尽管有高活性的抗逆转录病毒疗法（HAART）和免疫应答，但HIV-1仍持续存在：有证据表明在HAART患者中出现了新型病毒库，并且有关于HIV-1病毒和精英抑制者免疫应答的特征。
6. CC-Chemokine Ligand 2 (CCL2) Suppresses High Density Lipoprotein (HDL) Internalization and Cholesterol Efflux via CC-Chemokine Receptor 2 (CCR2) Induction and p42/44 Mitogen-activated Protein Kinase (MAPK) Activation in Human Endothelial Cells [O] . Run-Lu Sun, Can-Xia Huang, Jin-Lan Bao, 2016

机译：CC-趋化因子配体2（CCL2）通过CC-趋化因子受体2（CCR2）诱导和p42 / 44丝裂原活化蛋白激酶（MAPK）激活抑制高密度脂蛋白（HDL）内在化和胆固醇外流。
7. A stable CC-chemokine receptor (CCR)-5 tropic virus is correlated with the persistence of HIV RNA at less than 2.5 copies in successfully treated naïve subjects. [O] . Parisi, SG, Andreis, S, Mengoli, C, 2013

机译：稳定的CC趋化因子受体（CCR）-5嗜性病毒与成功治疗过的未治疗个体中HIV RNA的持久性低于2.5拷贝有关。
8. Quantitative Relationship of Circulating p24 Antigen with Human ImmunodeficiencyVirus (HIV) RNA and Specific Antibody in HIV-Infected Subjects Receiving Antiretroviral Therapy [R] . Brown, A. E., Vahey, M. T., Zhou, S. Y., 1995

机译：接受抗逆转录病毒治疗的HIV感染者循环p24抗原与人类免疫缺陷病毒（HIV）RNa和特异性抗体的定量关系

A stable CC-chemokine receptor (CCR)-5 tropic virus is correlated with the persistence of HIV RNA at less than 2.5 copies in successfully treated naïve subjects

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