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Uterine Malignant Mixed Müllerian Tumors Following Treatment with Selective Estrogen Receptor Modulators in Patients with Breast Cancer: A Report of 13 Cases and Their Clinicopathologic Characteristics

机译：选择性雌激素受体调节剂治疗乳腺癌患者的子宫恶性混合苗勒勒瘤：13例病例报告及临床病理特征

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BackgroundBreast cancer treatment with selective estrogen receptor modulators (SERMs) increases the incidence of uterine malignant mixed Müllerian tumors (uMMMTs). We examine clinicopathologic characteristics and prognosis of SERM-associated uMMMTs (S-uMMMTs) and discuss possible pathogenetic mechanisms.

机译：背景技术使用选择性雌激素受体调节剂（SERM）进行的乳腺癌治疗会增加子宫恶性混合苗勒氏瘤（uMMMTs）的发病率。我们检查与SERM相关的uMMMTs（S-uMMMTs）的临床病理特征和预后，并讨论可能的致病机制。

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期刊名称 Journal of Pathology and Translational Medicine
作者
Byung-Kwan Jeong; Chang O. Sung; Kyu-Rae Kim;
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作者单位

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年(卷),期 2019(53),1
年度 2019
页码 31–39
总页数 9
原文格式 PDF
正文语种
中图分类病理学;
关键词
Malignant Müllerian mixed tumor Selective estrogen receptor modulators Tamoxifen Breast neoplasm p53;

机译：恶性缪勒氏混合瘤;选择性雌激素受体调节剂;他莫昔芬;乳腺肿瘤;p53;

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专利

1. Uterine carcinosarcoma/malignant mixed Müllerian tumor incidence is increased in women with breast cancer, but independent of hormone therapy [J] . Wilson Brian T., Cordell Heather J. Journal of Gynecologic Oncology . 2015,第4期

机译：乳腺癌女性子宫癌肉瘤/恶性混合苗勒氏瘤发病率增加，但与激素治疗无关
2. Recurrent uterine tumors resembling ovarian sex-cord tumors with the growth regulation by estrogen in breast cancer 1-nuclear receptor coactivator 2 fusion gene: a case report and literature review [J] . Bin Chang, Qianming Bai, Lin Liang, Diagnostic pathology . 2020,第1期

机译：复发性子宫肿瘤类似于卵巢性脐带肿瘤，乳腺癌中雌激素的生长调节1核受体共同患者2融合基因：案例报告和文献综述
3. Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group. [J] . Colleoni M, Bonetti M, Coates AS, Journal of Clinical Oncology . 2000,第3期

机译：对于不表达雌激素受体的绝经前乳腺癌患者，尽早开始辅助化疗可能会改善治疗效果。国际乳腺癌研究小组。
4. Estrogen Receptors and Selective Estrogen Receptor Modulators in Bladder Cancer [C] . Kristi Hoffman, Carolyn L. Smith ^dgt, Baylor College of Medicine, Genitourinary Cancers Symposium . 2012

机译：膀胱癌中雌激素受体和选择性雌激素受体调节剂
5. The effects of the selective estrogen receptor modulators MPP and raloxifene in normal and cancerous human and murine uterine tissue. [D] . Davis, Angela Marie. 2007

机译：选择性雌激素受体调节剂MPP和雷洛昔芬在正常和癌变的人和鼠子宫组织中的作用。
6. Tamoxifen in breast cancer ipse dixit in uterine malignant mixed Müllerian tumor and sarcoma—A report of 8 cases and review of the literature [O] . Ana Luisa Cardoso Vasconcelos, Beatriz Nunes, Catarina Duarte, 2013

机译：他莫昔芬在子宫恶性混合苗勒氏肉瘤和子宫肉瘤的乳腺癌患者中的安全性－附8例报告并文献复习
7. Tamoxifen in breast cancer ipse dixit in uterine malignant mixed Müllerian tumor and sarcoma—A report of 8 cases and review of the literature [O] . Vasconcelos Ana Luisa Cardoso, Nunes Beatriz, Duarte Catarina, 2013

机译：他莫昔芬在子宫恶性混合苗勒氏肉瘤和子宫肉瘤的乳腺癌患者中的安全性－附8例报告并文献复习

Uterine Malignant Mixed Müllerian Tumors Following Treatment with Selective Estrogen Receptor Modulators in Patients with Breast Cancer: A Report of 13 Cases and Their Clinicopathologic Characteristics

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