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Anti-TNF- αtreatment-related pathways and biomarkers revealed by transcriptome analysis in Chinese psoriasis patients

机译：转录组分析揭示中国牛皮癣患者抗TNF-α治疗相关途径和生物标志物

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摘要

BackgroundAnti-tumor necrosis factor alpha (TNF- α) therapy has made a significant impact on treating psoriasis. Despite these agents being designed to block TNF- α activity, their mechanism of action in the remission of psoriasis is still not fully understood at the molecular level.

机译：背景抗肿瘤坏死因子α（TNF-α）治疗对牛皮癣的治疗产生了重大影响。尽管设计了这些试剂来阻断TNF-α的活性，但在分子水平上仍未完全了解其在缓解牛皮癣中的作用机理。

著录项

期刊名称 BMC Systems Biology
作者
Lunfei Liu; Wenting Liu; Yuxin Zheng; Jisu Chen; Jiong Zhou; Huatuo Dai; Suiqing Cai; Jianjun Liu; Min Zheng; Yunqing Ren;
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作者单位

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年(卷),期 2019(13),Suppl 2
年度 2019
页码 29
总页数 9
原文格式 PDF
正文语种
中图分类生物学;
关键词
Psoriasis Anti-tumor necrosis factor alpha (TNF- α) treatment Etanercept Peripheral blood mononuclear cells (PBMCs);

机译：银屑病;抗肿瘤坏死因子α（TNF-α）治疗;依那西普;外周血单个核细胞（PBMC）;

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专利

1. Anti-TNF- α treatment-related pathways and biomarkers revealed by transcriptome analysis in Chinese psoriasis patients [J] . Lunfei Liu, Wenting Liu, Yuxin Zheng, BMC Systems Biology . 2019,第2期

机译：转录组分析揭示中国银屑病患者抗TNF-α治疗相关途径和生物标志物
2. Analysis of Peripheral Blood Cells' Transcriptome in Patients With Subarachnoid Hemorrhage From Ruptured Aneurysm Reveals Potential Biomarkers [J] . Zhao Hua, Li Shi-ting, Zhu Jin, World neurosurgery . 2019,第期

机译：来自破裂动脉瘤蛛网膜下腔出血患者外周血细胞转录组的分析显示潜在的生物标志物
3. Intergrative methylome and transcriptome analysis to dissect key biological pathways for psoriasis in Chinese Han population [J] . Tang L., Cheng Y., Zhou F., The Journal of investigative dermatology. . 2018,第5a19期

机译：一体化甲基杂物和转录组分析，对中国汉族牛皮癣进行关联生物途径
4. Anti-TNF -a treatment-related pathways and biomarkers revealed by transcriptome analysis in Chinese psoriasis patients [C] . Asia Pacific Bioinformatics Conference . 2019

机译：抗TNF -A治疗相关的途径和生物标志物，在中国牛皮癣患者转录组分析显示
5. Blood and liver biomarkers and transcriptome alterations during the transition period reveal beneficial effects of rumen-protected methionine supplementation on health status and performance in dairy cows. [D] . Osorio Estevez, Johan Samir. 2014

机译：在过渡期间的血液和肝脏生物标志物以及转录组变化显示，瘤胃保护蛋氨酸补充对奶牛健康状况和生产性能的有益影响。
6. Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α [O] . Ane Langkilde, Lene C. Olsen, Pål Sætrom, 2011

机译：阿达木单抗治疗后牛皮癣患者皮肤的通路分析揭示了抗TNF-α抗炎机制的新的早期事件
7. Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. [O] . Ane Langkilde, Lene C Olsen, Pål Sætrom, 2016

机译：阿达木单抗治疗后银屑病患者皮肤的通路分析揭示了抗TNF-α抗炎机制的新早期事件。

Anti-TNF- αtreatment-related pathways and biomarkers revealed by transcriptome analysis in Chinese psoriasis patients

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