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Acute ischaemic stroke outcomes following mechanical thrombectomy in the elderly versus their younger counterpart: a retrospective cohort study

机译:老年人与年轻人相比机械血栓切除术后急性缺血性中风的预后:一项回顾性队列研究

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摘要

ObjectivesMany physicians debate the efficacy of mechanical thrombectomy for ischaemic stroke, but most agree that to establish potential benefit, patient selection must be examined further. People >80 years are a growing population of patients with ischaemic stroke but are largely excluded from clinical trials. The benefit of thrombectomy for them may be greatly reduced due to diminishing neuroplasticity and a larger number of medical comorbidities. To address this knowledge gap, we examined clinical and economic outcomes after mechanical thrombectomy in the ischaemic stroke population from the Nationwide Inpatient Sample. Our null hypotheses were that elderly patients (>80 years) would have a similar rate of inpatient mortality in comparison to their younger counterparts and incur a similar economic expense.
机译:目的许多医生争论机械血栓切除术对缺血性中风的疗效,但大多数人同意要确定潜在的益处,必须进一步检查患者的选择。 80岁以上的人群是缺血性中风患者的不断增加,但在临床试验中却被排除在外。由于神经可塑性的下降和大量的合并症,血栓切除术对他们的益处可能会大大降低。为了解决这一知识鸿沟,我们从全国住院患者样本中对缺血性卒中人群进行了机械血栓切除术后的临床和经济结果进行了检查。我们的零假设是,老年患者(> 80岁)与年轻患者相比,住院死亡率相似,并且产生相似的经济支出。

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