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An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk

机译：激素受体阴性和三阴性乳腺癌转移风险的优化的五基因多平台预测因子

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IntroductionOutcome predictors in use today are prognostic only for hormone receptor-positive (HRpos) breast cancer. Although microarray-derived multigene predictors of hormone receptor-negative (HRneg) and/or triple negative (Tneg) breast cancer recurrence risk are emerging, to date none have been transferred to clinically suitable assay platforms (for example, RT-PCR) or validated against formalin-fixed paraffin-embedded (FFPE) HRneg/Tneg samples.

机译：简介当前使用的结果预测因子仅对激素受体阳性（HRpos）乳腺癌具有预后作用。尽管微阵列来源的激素受体阴性（HRneg）和/或三阴性（Tneg）乳腺癌复发风险的多基因预测因子正在出现，但迄今为止，尚未将其转移到临床上合适的测定平台（例如RT-PCR）或经过验证针对福尔马林固定石蜡包埋（FFPE）HRneg / Tneg样品。

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期刊名称 Breast Cancer Research : BCR
作者
Christina Yau; John Sninsky; Shirley Kwok; Alice Wang; Amy Degnim; James N Ingle; Cheryl Gillett; Andrew Tutt; Fred Waldman; Dan Moore; Laura Esserman; Christopher C Benz;
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年(卷),期 2013(15),5
年度 2013
页码 R103
总页数 14
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk [J] . Christina Yau, John Sninsky, Shirley Kwok, Breast Cancer Research . 2013,第5期

机译：激素受体阴性和三阴性乳腺癌转移风险的优化的五基因多平台预测因子
2. A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer [J] . Christina Yau, Laura Esserman, Dan H Moore, Breast Cancer Research . 2010,第5期

机译：早期激素受体阴性和三阴性乳腺癌转移结果的多基因预测因子
3. Triple-negative breast cancers: Associations between imaging and pathological findings for triple-negative tumors compared with hormone receptor-positive/human epidermal growth factor receptor-2-negative breast cancers [J] . Boisserie-LacroixM., MacGroganG., DebledM., The oncologist . 2013,第7期

机译：三阴性乳腺癌：与激素受体阳性/人表皮生长因子受体-2-阴性乳腺癌相比，三阴性肿瘤的影像学表现与病理结果之间的关联
4. Proteomics of Benign and Metastatic Triple Negative Breast Cancer Cells and Cybrids [C] . Vadiraja Bhat, Durairaj Renu, Akanksha Mishra, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：良性和转移性三重阴性乳腺癌细胞和糖的蛋白质组学
5. Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer [D] . Yomtoubian, Shira. 2020

机译：EZH2催化活性的抑制选择性地靶向三阴性乳腺癌中的转移性亚群
6. A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer [O] . Christina Yau, Laura Esserman, Dan H Moore, 2010

机译：早期激素受体阴性和三阴性乳腺癌转移结果的多基因预测因子
7. An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk [O] . Christina Yau, John Sninsky, Shirley Kwok, 2013

机译：激素受体阴性和三阴性乳腺癌转移风险的优化的五基因多平台预测因子
8. Novel Differentiation Therapy Approach to Reduce the Metastatic Potential of Basal, Highly Metastatic, Triple-Negative Breast Cancers. [R] . Chu, I. 2012

机译：新型分化治疗方法降低基底，高转移性，三阴性乳腺癌的转移潜能。

An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk

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