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Tuberculosis mortality in Finland

机译:芬兰的结核病死亡率

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摘要

The present report, analysing the official statistics on tuberculosis mortality in Finland during the past 75 years, was undertaken to provide a background for studying the course of tuberculosis after the nation-wide BCG vaccination campaign of 1948-49.Tuberculosis mortality in Finland has been high compared with other European countries: before the end of the first World War the death-rate from respiratory tuberculosis fluctuated between 250 and 300 per 100,000; by 1953 it had dropped to 56 for males and 27 for females.Age-specific death-rates for respiratory tuberculosis usually showed peaks for infancy, young adulthood, and old age. For many years the highest mortality-rates for females were in young adulthood, and a high proportion of all deaths from respiratory tuberculosis, in both males and females, was in the age-group 15-40 years. Tuberculosis proportionate mortality was also high in this age-group: 30%-50% for males and 40%-60% for females. In recent years the pattern has changed, the “weight” in the age distribution of the number of deaths has shifted towards higher ages.The death-rates for non-respiratory tuberculosis, with tuberculous meningitis the most important, are several times higher in infancy than the rates for respiratory tuberculosis. Non-respiratory tuberculosis is of little importance in adults.The cohort curves for respiratory tuberculosis differ in two important ways from the classic curves for Massachusetts. The peaks of the Finnish curves in adult ages shift to lower ages with each succeeding cohort, and the curves often cross each other.Tuberculosis mortality in Finland, as in almost every other country, has decreased very rapidly since the second World War, particularly in the younger age-groups. However, as a similar pattern is found in countries where BCG has not been used, there seems to be little compelling evidence to support a belief that the nation-wide BCG programme caused much, if any, of the recent precipitous drop in mortality-rates. Other factors having a strong influence on tuberculosis mortality have undoubtedly been operating in Finland as almost everywhere.
机译:本报告分析了过去75年芬兰的官方结核病死亡率统计数据,为研究1948-49年全国BCG疫苗接种运动之后的结核病病程提供了背景资料。与其他欧洲国家相比要高:第一次世界大战结束前,呼吸系统结核病的死亡率在每10万人中250至300人之间波动;到1953年,男性的死亡率已降至56岁,女性为27岁。呼吸道结核病的特定年龄死亡率通常在婴儿期,成年期和老年期达到峰值。多年来,女性的死亡率最高是成年后的年龄,而在男性和女性中,由呼吸道结核引起的所有死亡中,很大的比例是在15至40岁之间。在这个年龄段,结核病的比例死亡率也很高:男性为30%-50%,女性为40%-60%。近年来,这种模式发生了变化,死亡人数在年龄分布中的“权重”已转向更高的年龄。非呼吸性结核病的死亡率以结核性脑膜炎为重,婴儿期的死亡率高出几倍。比呼吸系统结核的发生率高。非呼吸结核在成年人中的重要性不高。呼吸结核的队列曲线与马萨诸塞州的经典曲线在两个重要方面有所不同。自第二次世界大战以来,芬兰和其他几乎每个国家一样,芬兰的结核病死亡率已迅速下降,尤其是在第二次世界大战之后年轻的年龄段。但是,由于在未使用BCG的国家中也发现了类似的情况,因此似乎没有令人信服的证据支持这样一种信念,即全国范围的BCG计划导致了近期死亡率的急剧下降(如果有的话) 。无疑,在芬兰几乎所有地方都在使用其他对结核病死亡率有重大影响的因素。

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