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Efficacy and safety of controlled-release oxycodonealoxone versus controlled-release oxycodone in Korean patients with cancer-related pain: a randomized controlled trial

机译:控释羟考酮/纳洛酮与控释羟考酮在韩国癌症相关性疼痛患者中的疗效和安全性:一项随机对照试验

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摘要

BackgroundControlled-release oxycodonealoxone (OXN-CR) maintains the effect of opioid-induced analgesia through oxycodone while reducing the occurrence rate of opioid-induced constipation through naloxone. The present study was designed to assess the non-inferiority of OXN-CR to controlled-release oxycodone (OX-CR) for the control of cancer-related pain in Korean patients.
机译:背景控释羟考酮/纳洛酮(OXN-CR)维持了通过阿昔康酮对阿片类药物引起的镇痛作用,同时降低了由纳洛酮引起的阿片类药物引起便秘的发生率。本研究旨在评估OXN-CR对控释羟考酮(OX-CR)的非劣效性,以控制韩国患者的癌症相关疼痛。

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