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Overexpression of COL5A1 promotes tumor progression and metastasis and correlates with poor survival of patients with clear cell renal cell carcinoma

机译：过度表达COL5A1促进肿瘤进展和转移并与透明细胞肾细胞癌患者的不良生存相关

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Background and aimsCOL5A1 has been identified to be involved in metastasis of clear cell renal cell carcinoma (ccRCC) by bioinformatic analysis. This study aimed to investigate COL5A1 expression and its clinical significance in ccRCC. The function of COL5A1 in ccRCC was further investigated.

机译：背景和目的通过生物信息学分析，已确定COL5A1参与了透明细胞肾细胞癌（ccRCC）的转移。本研究旨在研究COL5A1在ccRCC中的表达及其临床意义。进一步研究了COL5A1在ccRCC中的功能。

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期刊名称 Cancer Management and Research
作者
Gang Feng; Hui-Min Ma; Hou-Bao Huang; Ya-Wei Li; Peng Zhang; Jian-Jun Huang; Long Cheng; Guo-Rong Li;
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作者单位

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年(卷),期 2019(11),-1
年度 2019
页码 1263–1274
总页数 12
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
clear cell renal cell carcinoma COL5A1 biomarkers prognosis;

机译：透明细胞肾细胞癌;COL5A1;生物标志物;预后;

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专利

1. Overexpression of the metastasis-associated gene MTA3 correlates with tumor progression and poor prognosis in hepatocellular carcinoma [J] . Wang Chuanxi, Li Guanzhen, Li Jiamei, Journal of gastroenterology and hepatology . 2017,第8期

机译：转移相关基因MTA3的过表达与肝细胞癌的肿瘤进展和预后差相相关
2. L1 cell adhesion molecule overexpression in hepatocellular carcinoma associates with advanced tumor progression and poor patient survival [J] . Xiaodong Guo, Lu Xiong, Lin Zou, Diagnostic pathology . 2012,第4期

机译：肝细胞癌中的L1细胞粘附分子过度表达与晚期肿瘤进展和患者生存不良有关
3. Downregulation of FOXO3a promotes tumor metastasis and is associated with metastasis-free survival of patients with clear cell renal cell carcinoma [J] . NiD., MaX., LiH.-Z., Clinical cancer research: an official journal of the American Association for Cancer Research . 2014,第7期

机译：FOXO3a的下调促进肿瘤转移，并与透明细胞肾细胞癌患者的无转移生存相关
4. FUNCTIONAL ASSAYS OF DRUG-TARGET ENGAGEMENT ON CIRCULATING TUMOR CELLS CAPTURED FROM PATIENT BLOOD CORRELATE WITH PATIENT PROGRESSION [C] . Brian J. Kirby, Erica D. Pratt, Steven M. Santana, International Conference on Miniaturized Systems for Chemistry and Life Sciences . 2011

机译：药物 - 目标接合的功能测定与患者血液捕获的循环肿瘤细胞与患者进展相关
5. Phosphatidylinositol Remodeling Through Membrane Bound O-Acyl Transferase Domain-7 (MBOAT7) Promotes the Progression of Clear Cell Renal Cell Carcinoma (ccRCC) [D] . Neumann, Chase K. A. 2020

机译：通过膜结合的磷脂酰肌醇通过膜结合O-酰基转移酶结构域-7（MBOAT7）促进透明细胞肾细胞癌的进展（CCRCC）
6. Overexpression of Ubiquitin-Specific Protease15 (USP15) Promotes Tumor Growth and Inhibits Apoptosis and Correlated With Poor Disease-Free Survival in Hepatocellular Carcinoma [O] . Xue-Qing Yao, Ling Li, Long-Zhen Piao, 2020

机译：特定泛素特异性蛋白酶15（USP15）的过度表达促进肿瘤生长并抑制细胞凋亡并与肝细胞癌的无疾病存活率相关
7. L1 cell adhesion molecule overexpression in hepatocellular carcinoma associates with advanced tumor progression and poor patient survival [O] . Xiaodong Guo, Lu Xiong, Lin Zou, 2012

机译：肝细胞癌中的L1细胞粘附分子过度表达与晚期肿瘤进展和患者生存不良有关

Overexpression of COL5A1 promotes tumor progression and metastasis and correlates with poor survival of patients with clear cell renal cell carcinoma

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