Randomized Phase III Trial of Irinotecan Plus Cisplatin versus Etoposide Plus Cisplatin in Chemotherapy-Naïve Korean Patients with Extensive-Disease Small Cell Lung Cancer

机译：伊立替康联合顺铂与依托泊苷联合顺铂在未经化疗的韩国广泛性疾病小细胞肺癌患者中进行的随机III期试验

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摘要

PurposeThis randomized phase III study was designed to compare the efficacy and safety of irinotecan plus cisplatin (IP) over etoposide plus cisplatin (EP) in Korean patients with extensive-disease small-cell lung cancer (SCLC).

机译：目的这项随机III期研究旨在比较伊立替康加顺铂（IP）相对于依托泊苷加顺铂（EP）在韩国大病小细胞肺癌（SCLC）患者中的疗效和安全性。

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期刊名称 Cancer Research and Treatment : Official Journal of Korean Cancer Association
作者
Dong-Wan Kim; Hoon-Gu Kim; Joo-Hang Kim; Keunchil Park; Hoon-Kyo Kim; Joung Soon Jang; Bong-Seog Kim; Jin-Hyoung Kang; Kyung Hee Lee; Sang-We Kim; Hun Mo Ryoo; Jin-Soo Kim; Ki Hyeong Lee; Jung Hye Kwon; Jin-Hyuk Choi; Sang Won Shin; Seokyung Hahn; Dae Seog Heo;
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作者单位

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年(卷),期 2019(51),1
年度 2019
页码 119–127
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Etoposide Irinotecan Cisplatin Small cell lung carcinoma Korean;

机译：依托泊苷;伊立替康;顺铂;小细胞肺癌;韩语;

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专利

1. Randomized phase III trial of cisplatin/irinotecan versus cisplatin/etoposide in patients with extensive-stage small-cell lung cancer. [J] . Lara-PN Jr, Gandara DR, Natale RB Clinical lung cancer . 2006,第5期

机译：顺铂/伊立替康与顺铂/依托泊苷在广泛期小细胞肺癌患者中的随机III期试验。
2. Open-label, multicenter, randomized, phase III study comparing oral topotecan/cisplatin versus etoposide/cisplatin as treatment for chemotherapy-naive patients with extensive-disease small-cell lung cancer. [J] . Eckardt JR, von Pawel J, Papai Z, Journal of Clinical Oncology . 2006,第13期

机译：开放标签，多中心，随机，III期研究，比较口服拓扑替康/顺铂与依托泊苷/顺铂作为初治广泛性小细胞肺癌患者的治疗。
3. Randomized phase III trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer. [J] . Hanna N, Bunn PA Jr, Langer C, Journal of Clinical Oncology . 2006,第13期

机译：III期随机试验比较了伊立替康/顺铂与依托泊苷/顺铂在以前未经治疗的广泛期疾病小细胞肺癌患者中的疗效。
4. THE INHIBITION OF N-LINKED GLYCOSYLATION BREAKS THE RESISTANACE OF HUMAN OVARIAN CANCER CELLS TO CISPLATIN AND ETOPOSIDE [C] . Anna Macieia, Joanna Sarnik, Zbigniew J. Witczak International Carbohydrate Symposium . 2018

机译：N-连接的糖基化的抑制破坏了人卵巢癌细胞对顺铂和依托泊苷的抗性
5. Yu Ping Feng San, an Ancient Chinese Herbal Decoction, Reverses Cisplatin-Induced Multi-Drug Resistance in Lung Cancer Cells: Mechanistic Evaluation and Development of New Formula [D] . Lou, Jianshu 2018

机译：俞平风散，一种古老的中药汤剂，逆转顺铂诱导的肺癌细胞多药耐药性：新药的机械评价和开发
6. Randomised phase II trial of irinotecan plus cisplatin vs irinotecan cisplatin plus etoposide repeated every 3 weeks in patients with extensive-disease small-cell lung cancer [O] . I Sekine, H Nokihara, K Takeda, 2008

机译：伊立替康加顺铂与伊立替康顺铂加依托泊苷的II期随机试验每3周重复一次用于广泛疾病小细胞肺癌患者
7. Randomised phase II trial of irinotecan plus cisplatin vs irinotecan, cisplatin plus etoposide repeated every 3 weeks in patients with extensive-disease small-cell lung cancer [O] . Sekine, I, Nokihara, H, Takeda, K, 2008

机译：伊利替康加顺铂与伊立替康，顺铂加依托泊苷的II期随机试验在大病小细胞肺癌患者中每3周重复一次

Randomized Phase III Trial of Irinotecan Plus Cisplatin versus Etoposide Plus Cisplatin in Chemotherapy-Naïve Korean Patients with Extensive-Disease Small Cell Lung Cancer

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