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GCAT-SEEKquence: Genome Consortium for Active Teaching of Undergraduates through Increased Faculty Access to Next-Generation Sequencing Data

机译:GCAT-SEEKquence:基因组联合会通过增加教师对下一代测序数据的访问积极开展本科生教学

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摘要

To transform undergraduate biology education, faculty need to provide opportunities for students to engage in the process of science. The rise of research approaches using next-generation (NextGen) sequencing has been impressive, but incorporation of such approaches into the undergraduate curriculum remains a major challenge. In this paper, we report proceedings of a National Science Foundation–funded workshop held July 11–14, 2011, at Juniata College. The purpose of the workshop was to develop a regional research coordination network for undergraduate biology education (RCN/UBE). The network is collaborating with a genome-sequencing core facility located at Pennsylvania State University (University Park) to enable undergraduate students and faculty at small colleges to access state-of-the-art sequencing technology. We aim to create a database of references, protocols, and raw data related to NextGen sequencing, and to find innovative ways to reduce costs related to sequencing and bioinformatics analysis. It was agreed that our regional network for NextGen sequencing could operate more effectively if it were partnered with the Genome Consortium for Active Teaching (GCAT) as a new arm of that consortium, entitled GCAT-SEEK(quence). This step would also permit the approach to be replicated elsewhere.
机译:为了转变本科生物学教学,教师需要为学生提供参与科学过程的机会。使用下一代(NextGen)测序的研究方法的兴起令人印象深刻,但是将这些方法整合到本科课程中仍然是一个重大挑战。在本文中,我们报告了2011年7月11日至14日在朱尼亚塔学院举行的美国国家科学基金会资助的研讨会的会议记录。研讨会的目的是为本科生生物学教育(RCN / UBE)建立一个区域研究协调网络。该网络正在与位于宾夕法尼亚州立大学(大学公园)的基因组测序核心设施合作,以使小型学院的本科生和教职员工能够使用最新的测序技术。我们旨在创建一个与NextGen测序相关的参考文献,协议和原始数据的数据库,并找到降低与测序和生物信息学分析相关的成本的创新方法。达成一致意见的是,如果我们与“主动教学基因组联盟”(GCAT)作为该联盟的新机构“ GCAT-SEEK(quence)”合作,则我们用于NextGen测序的区域网络可以更有效地运作。此步骤还将允许将该方法复制到其他地方。

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