Lack of effect of methotrexate in budesonide-refractory collagenous colitis

摘要

BackgroundIn most cases, collagenous colitis can be treated effectively with budesonide. However, some patients develop side effects or have chronic symptoms refractory to budesonide. This paper reports an open case series of patients intolerant or refractory to budesonide who were treated with methotrexate (MTX).