首页> 美国卫生研究院文献>Clinical Cosmetic and Investigational Dentistry >Effects of desensitizing dentifrices on the reduction of pain sensitivity caused by in-office dental whitening: a double-blind controlled clinical study
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Effects of desensitizing dentifrices on the reduction of pain sensitivity caused by in-office dental whitening: a double-blind controlled clinical study

机译:脱敏洁齿剂对减少办公室内牙齿美白引起的疼痛敏感性的影响:双盲对照临床研究

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摘要

>Objective: The purpose of this study was to clinically evaluate the influence of desensitizing dentifrices applied through a plastic tray on reducing the pain sensitivity and color variation caused by in-office dental whitening and to evaluate differences among such dentifrices through a controlled double-blind clinical study.>Materials and methods: A prospective study was conducted with 48 individuals between 18 and 30 years without gender distinction. For the dental whitening, 35% hydrogen peroxide was used in three clinical sessions. After each whitening session, the volunteers used a plastic tray containing one of the dentifrices (sucralose– S, sodium fluoride – SF, arginine and calcium carbonate – ACC, and 5% potassium nitrate – PN) for 4 hrs during the night. The evaluation of the sensitivity associated with the use of the plastic tray in each whitening session was performed using the analog numerical scale with scores from 0 to 10. The color variation (ΔE) was determined with a spectrophotometer. The pain sensitivity data were submitted to the multivariate analysis of variance with repeated measurements and a Lambda Wilks test (p<0.05). To analyze the color variation, a one-way ANOVA was applied (p<0.05).>Results: The ACC and 5% NP groups showed a reduction in sensitivity in relation to the other groups (p<0.05). There was a reduction in sensitivity after placement of the tray with dentifrice. The color evaluation associated with the dentifrice showed no difference (p=0.9186).>Conclusion: The use of desensitizing dentifrices with ACC or 5% NP in a plastic tray was effective for the reduction of pain sensitivity, and the use of a desensitizing dentifrice did not decrease the effectiveness of whitening.
机译:>目的:该研究的目的是临床评估通过塑料托盘施加的脱敏牙膏对减少办公室内牙齿增白引起的疼痛敏感性和颜色变化的影响,并评估这些牙膏之间的差异。通过一项受控的双盲临床研究。>材料和方法:前瞻性研究针对48位年龄在18至30岁之间且无性别差异的个体进行。对于牙齿增白,在三个临床阶段中使用了35%的过氧化氢。每次美白疗程后,志愿者在一个装有塑料粉的托盘中放置了4小时,该托盘装有一种牙粉(三氯蔗糖– S,氟化钠– SF,精氨酸和碳酸钙– ACC,以及5%硝酸钾– PN)。使用分数从0到10的模拟数字刻度对与每次使用美白塑料托盘相关的灵敏度进行评估。用分光光度计确定颜色变化(ΔE)。疼痛敏感性数据通过重复测量和Lambda Wilks检验提交给方差的多变量分析(p <0.05)。为了分析颜色变化,应用单向方差分析(p <0.05)。>结果: ACC组和5%NP组相对于其他组显示出敏感性降低(p <0.05 )。用牙粉放置托盘后,灵敏度降低。与洁牙剂相关的颜色评估没有差异(p = 0.9186)。>结论:在塑料托盘中使用ACC或5%NP的脱敏牙膏可有效降低疼痛敏感性,并且使用脱敏洁齿剂不会降低美白效果。

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