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Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?

机译:大脑未加工:是否在败血症中发现了BNP的作用例如将方形钉插入圆孔中?

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摘要

Since its introduction to the intensive care setting a decade ago, B-type natriuretic peptide has been the focus of studies in different areas (in particular, sepsis). With this biomarker, as with many newly identified biomarkers, its diagnostic performance was pursued initially and then its ability to predict outcomes. Despite all the efforts, results have not been consistent and the applications of B-type natriuretic peptide in the intensive care setting remain by and large academic. Will such studies one day become clinical practice? Or are we too obsessed with finding a place for every biomarker?
机译:自从10年前将其引入重症监护以来,B型利钠肽一直是不同领域(尤其是败血症)研究的重点。与许多新近鉴定的生物标志物一样,这种生物标志物首先要追求其诊断性能,然后才具有预测结果的能力。尽管付出了所有努力,但结果仍不一致,B-型钠尿肽在重症监护室中的应用仍被广泛学术研究。这样的研究有一天会成为临床实践吗?还是我们太着迷于为每个生物标记物寻找位置?

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