Comprehensive investigation of clinicopathologic features oncogenic driver mutations and immunohistochemical markers in peripheral lung squamous cell carcinoma

摘要

BackgroundAlthough the majority of lung squamous cell carcinomas (SQCC) arise in central airways, the prevalence of peripheral (p) SQCC is increasing. This study aimed to have a comprehensive investigation of clinicopathologic features, status of common driver mutations and immunophenotypes of p-SQCC compared to central (c) SQCC.