Blood-based Nutritional Risk Index for Cognition in the Nutrition and Brain Aging Study (NBAS): Emphasis on n-3 PUFA Vitamin D and Homocysteine (P14-005-19)

摘要

ObjectivesNutrients and their metabolites have interactive qualities that may be harnessed for prevention of cognitive decline. Simultaneous modulation of one-carbon, fatty acid and vitamin D metabolism (25-OH-D) may offer neuroprotection. We examined whether n-3 polyunsaturated fatty acids (n-3 PUFA), 25-OH-D, and homocysteine (HCy) formed into a Nutritional Risk Index (NRI) can explain cognitive performance of older non-demented adults.