Interaction Between Dietary Choline Intake During Pregnancy and Choline-metabolising Genetic Polymorphisms on the Risk of Preterm Birth (P11-037-19)

摘要

ObjectivesAdequate intake of dietary choline, an essential nutrient, is pivotal for an optimal pregnant outcome and fetal programming, which may be affected by choline-metabolising genetic polymorphisms. This case-control study aims to investigate the interaction between choline intake during pregnancy and genetic polymorphisms in choline dehydrogenase (CHDH) and betaine-homocysteine methyltransferase (BHMT) on preterm birth risk among Chinese women.