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Data on chow liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6–24 weeks

机译:在给小鼠喂食西方饮食6至24周后其食物肝脏组织和线粒体脂肪酸组成以及线粒体蛋白质组变化的数据

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摘要

The data presented in this article describe the fatty acid composition of chow, liver tissue and isolated liver mitochondria from mice fed for 6–24 weeks with a high caloric western diet (WD) in comparison to control diet (normal diet, ND). The fatty acid composition was measured via gas chromatography flame ionization detection (GC-FID). Moreover, WD-induced mitochondrial protein changes are presented in this work and were analyzed by mass spectrometry (LC–MS/MS). For further interpretation and discussion of the presented data please refer to the research article entitled “Mitochondrial adaptation in steatotic mice” (Einer et al., 2017) .
机译:本文提供的数据描述了饲喂高热量西式饮食(WD)6至24周的小鼠与对照饮食(正常饮食,ND)相比,食物,肝脏组织和分离的肝线粒体的脂肪酸组成。通过气相色谱火焰离子化检测(GC-FID)测量脂肪酸组成。此外,WD诱导的线粒体蛋白质变化已在这项工作中提出,并通过质谱分析(LC-MS / MS)进行了分析。有关所提供数据的进一步解释和讨论,请参阅研究文章“脂肪变性小鼠中的线粒体适应”(Einer等人,2017)。

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