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Multi-modality imaging review of congenital abnormalities of kidney and upper urinary tract

机译:肾脏和上尿路先天性异常的多模式影像学检查

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摘要

Congenital abnormalities of the kidney and urinary tract (CAKUT) include a wide range of abnormalities ranging from asymptomatic ectopic kidneys to life threatening renal agenesis (bilateral). Many of them are detected in the antenatal or immediate postnatal with a significant proportion identified in the adult population with varying degree of severity. CAKUT can be classified on embryological basis in to abnormalities in the renal parenchymal development, aberrant embryonic migration and abnormalities of the collecting system. Renal parenchymal abnormalities include multi cystic dysplastic kidneys, renal hypoplasia, number (agenesis or supernumerary), shape and cystic renal diseases. Aberrant embryonic migration encompasses abnormal location and fusion anomalies. Collecting system abnormalities include duplex kidneys and Pelvi ureteric junction obstruction. Ultrasonography (US) is typically the first imaging performed as it is easily available, non-invasive and radiation free used both antenatally and postnatally. Computed tomography (CT) and magnetic resonance imaging (MRI) are useful to confirm the ultrasound detected abnormality, detection of complex malformations, demonstration of collecting system and vascular anatomy and more importantly for early detection of complications like renal calculi, infection and malignancies. As CAKUT are one of the leading causes of end stage renal disease, it is important for the radiologists to be familiar with the varying imaging appearances of CAKUT on US, CT and MRI, thereby helping in prompt diagnosis and optimal management.
机译:肾和泌尿系统的先天性异常包括范围广泛的异常,从无症状的异位肾到威胁生命的肾发育不全(双侧)。其中许多是在产前或产后立即检测到的,在成年人群中发现的比例很高,严重程度不同。可以根据胚胎学将CAKUT分类为肾实质发育异常,异常的胚胎迁移和收集系统异常。肾实质异常包括多囊性增生性肾脏,肾发育不全,数量(发育不全或多胎),形状和囊性肾脏疾病。异常的胚胎迁移包括异常的位置和融合异常。收集系统异常包括双肾和盆腔输尿管连接阻塞。超声检查(US)通常是首先进行的成像,因为它在产前和产后均易于获得,无创且无辐射。计算机断层扫描(CT)和磁共振成像(MRI)可用于确认超声检测到的异常,检测复杂的畸形,展示收集系统和血管解剖结构,更重要的是可用于早期发现并发症,例如肾结石,感染和恶性肿瘤。由于CAKUT是终末期肾脏疾病的主要原因之一,因此放射科医生必须熟悉CAKUT在US,CT和MRI上不同的影像学表现,从而有助于迅速诊断和最佳管理。

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