Primary Immunodeficiency: 545 Global Prevalence and Types of Autoimmune Diseases Found in Children with Primary Immunodeficiencies; A Single-Center Experience

摘要

BackgroundAutoimmune manifestations in primary immunodeficiencies (PIDs) are not uncommon, and they are more frequently observed in defects affecting lymphocytes and their regulatory mechanisms. There is a wide variability in prevalence, ranging from immune defects in which autoimmunity defines the syndrome, others with a very high prevalence of autoimmune manifestations, defects with a moderate prevalence, and those in which autoimmunity is rather an exception than the rule.