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Allergy to Antimicrobials: 260 Association Between Genetic Polymorphisms of ABCC2 Transporter and the Susceptibility to Maculopapular Eruption Induced by Antituberculosis Drugs

机译：对抗生素过敏：260 ABCC2转运蛋白基因多态性与抗结核药物引起的斑疹性爆发的敏感性之间的关联

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BackgroundATP-binding cassette (ABC) transporter proteins play an important role in drug disposition. Polymorphisms of ABC transporter genes (ABCC2 and ABCB1) may be risk markers for maculopapular eruption (MPE) induced by unusual accumulation of antituberculosis drugs (ATD) itself or metabolites.

机译：背景ATP结合盒（ABC）转运蛋白在药物处置中起重要作用。 ABC转运蛋白基因（ABCC2和ABCB1）的多态性可能是由抗结核药物（ATD）本身或代谢产物的异常蓄积引起的斑丘疹爆发（MPE）的危险标志。

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期刊名称 The World Allergy Organization Journal
作者
Sang-Hoon Kim; Sang-Heon Kim; Jae-Hyung Lee; Byoung-Hoon Lee; Young-Koo Jee;
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年(卷),期 2012(5),Suppl 2
年度 2012
页码 S102
总页数 1
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1. ABCC2 Haplotype is Associated With Antituberculosis Drug-Induced Maculopapular Eruption [J] . Kim Sang-Heon, Jee Young-Koo, Lee Jae-Hyung, Allergy, Asthma & Immunology Research . 2012,第6期

机译：ABCC2单倍型与抗结核药物诱导的斑丘疹爆发相关
2. Polymorphisms in drug transporter genes (ABCB1, SLCO1B1 and ABCC2) and hepatitis induced by antituberculosis drugs [J] . KimS.-H., LeeJ.-H., LeeB.-H., Tuberculosis . 2012,第1期

机译：抗结核药物诱导的药物转运蛋白基因（ABCB1，SLCO1B1和ABCC2）和肝炎的多态性
3. Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population [J] . Pan Hongqiu, Yang Miaomiao, Lu Lihuan, Pharmacogenetics and genomics . 2019,第4期

机译：FAM65B，AGBL4和CUX2遗传多态性与易患抗亚偶曲霉药物诱发的肝毒性的关联：中国汉族人群的验证研究
4. Exploring genetic variability in drug therapy by selecting a minimum subset of the most informative single nucleotide polymorphisms through approximation of a markov blanket in a kernel-induced space [C] . Lou Qiang, Parkman Henry P., Jacobs Michael R., Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2012 IEEE Symposium on . 2012

机译：通过在籽粒诱导的空间中通过近似马可夫毯选择最丰富的单核苷酸多态性的最小子集来探索药物治疗中的遗传变异性
5. CYP2E1 GSTM1 and GSTT1 genetic polymorphisms and their associations with susceptibility to antituberculosis drug-induced liver injury in Thai tuberculosis patients [O] . Noppadol Chanhom, Sukanya Wattanapokayakit, Nusara Satproedprai, 2021

机译：CYP2E1GSTM1和GSTT1遗传多态性及其与敏感性抗性药物诱导的泰国结核病患者肝损伤的关联
6. Association of Genetic Polymorphism of GSTM1 and GSTT1 with the Susceptibility to Antituberculosis Drug-induced Hepatotoxicity in Chinese Population [O] . Gang Xiao 2018

机译：GSTM1和GSTT1遗传多态性与抗亚霉菌药物诱导的中国人群肝毒性的缔合物

Allergy to Antimicrobials: 260 Association Between Genetic Polymorphisms of ABCC2 Transporter and the Susceptibility to Maculopapular Eruption Induced by Antituberculosis Drugs

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