Patho-Biology of Nasal Polyps: 130 Mutiplex Analyses of Cytokine and Chemokine Release From the Cultured Fibroblast of Nasal Polyp: the Effect of IL-17A

摘要

BackgroundNasal polyps of chronic rhinosinusitis (CRS) are characterized by epithelial damage, basement membrane thickness and subepithelial fibrosis. The fibroblast, one of the main cell types making up nasal polyps, is thought to be a target cell of various cytokines. The role of IL-17A in immunoresponse in the nasal poly fibroblast has not yet elucidated.