THERAPEUTIC AGENT FOR NASAL POLYP AND EDEMATOUS LESION OF NASAL MUCOUS MEMBRANE

摘要

PROBLEM TO BE SOLVED: To obtain a therapeutic agent for nasal polyp and edematous lesions of the nasal mucous membrane that contains aspirin as an effective agent and is directly applied to the affected part. ;SOLUTION: This therapeutic agent for nasal polyp and edematous lesions of the nasal mucous membrane, which contains aspirin or its salt as an effective agent in the form of powder, is directly applied to the affected part by spray, inhalation, coating, etc. The aspirin is preferably applied in the form of its salt, preferably DL-lysine salt of aspirin. The most suitable form of this therapeutic agent is powder that passes a screen of 200 mesh (75μm). The direct application assures action of the agent in high concentration, and shows excellent effects such as contraction or disappearance of nasal polyp when the nasal polyp is in the stage of edematous lesion or in the initial stage of nasal polyp formation by applying the agent to the affected part twice or three times a day in dosage of 10-1,000mg, preferably 50-100mg, on the basis of aspirin or its salt.;COPYRIGHT: (C)1998,JPO