Allergen Structure 1: 13 Gene Expression Pattern of Arabidopsis EXPB1 a Nonallergenic Homologue of Grass Group 1 Pollen Allergens

摘要

BackgroundGrass pollen allergy is one of the most common allergies worldwide. Group I allergens constitute the major allergenic component of grass pollen with more than 85% of grass pollen allergic patients showing IgE reactivity. These are highly immunologically cross-reactive glycoproteins specifically expressed in pollen of all grasses. Alignments of the amino-acid sequences of grass group I allergens derived from diverse grass species reveal up to 95% homology. It is therefore likely that these molecules share a similar biological function.