Prognostic Value of miRNA-155 Expression in B-Cell Non-Hodgkin Lymphoma

机译：miRNA-155表达在B细胞非霍奇金淋巴瘤中的预后价值

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摘要

Objective:MicroRNA-155 (miRNA-155) resides within the B-cell integration cluster gene on chromosome 21. It can act either as an oncogene or as a tumor-suppressor gene, depending on the cell background in which miRNA-155 is performing its specific target gene controlling function. Therefore, the aim of this study was to investigate miRNA-155 expression in patients with B-cell non-Hodgkin lymphoma (NHL) and its relation to disease prognosis in diffuse large B-cell lymphoma (DLBCL) patients.

机译：目的：MicroRNA-155（miRNA-155）位于21号染色体上的B细胞整合簇基因内。它可以作为癌基因或抑癌基因，这取决于miRNA-155所处的细胞背景其特异的靶基因控制功能。因此，本研究的目的是调查弥漫性大B细胞淋巴瘤（DLBCL）患者在B细胞非霍奇金淋巴瘤（NHL）患者中的miRNA-155表达及其与疾病预后的关系。

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期刊名称 Turkish Journal of Hematology
作者
Ahmed M. L. Bedewy; Shereen M. Elmaghraby; Ahmed A. Shehata; Noha S. Kandil;
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作者单位

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年(卷),期 2017(34),3
年度 2017
页码 207–212
总页数 6
原文格式 PDF
正文语种
中图分类血液学检验;
关键词
MicroRNA-155 non-Hodgkin lymphoma prognosis;

机译：MicroRNA-155;非霍奇金淋巴瘤;预后;

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专利

1. Prognostic Value of miRNA-155 Expression in B-Cell Non-Hodgkin Lymphoma [J] . Ahmed M. L. Bedewy, Shereen M. Elmaghraby, Ahmed A. Shehata, Turkish Journal of Hematology . 2017,第3期

机译：miRNA-155表达在B细胞非霍奇金淋巴瘤中的预后价值
2. Lack of prognostic significance of BCL2 and p53 protein overexpression in elderly patients with diffuse large B-cell non-Hodgkin's lymphoma: results from a population-based non-Hodgkin's lymphoma registry. [J] . Maartense E, Kramer MH, le Cessie S, Leukemia and lymphoma . 2004,第1期

机译：老年弥漫性大B细胞非霍奇金淋巴瘤患者中BCL2和p53蛋白过表达的预后意义缺乏：基于人群的非霍奇金淋巴瘤登记的结果。
3. Differential expression of enhancer of zeste homolog 2 (EZH2) protein in small cell and aggressive B-cell non-Hodgkin lymphomas and differential regulation of EZH2 expression by p-ERK1/2 and MYC in aggressive B-cell lymphomas [J] . Xuejun Tian, Ashley Pelton, Ali Shahsafaei, Modern Pathology . 2016,第9期

机译：zeste同源2（EZH2）蛋白增强子在小细胞和侵袭性B细胞非霍奇金淋巴瘤中的差异表达以及p-ERK1 / 2和MYC对侵袭性B细胞淋巴瘤中EZH2表达的差异调节
4. Expression profile of HIP1R in B-cell subsets and in silico prediction of its functions in diffuse large B-cell lymphoma [C] . Kah Keng Wong, Alison H Banham International Conference on Intelligent Informatics and Biomedical Sciences . 2018

机译：HIP1R在B细胞亚群中的表达特征及其在弥漫性大B细胞淋巴瘤中的功能的计算机预测
5. Regulation of CD20 in rituximab-resistant cell lines (RRCL) and B-cell non-Hodgkin's lymphoma (B-NHL) [D] . Tsai, Ping-Chiao 2012

机译：CD20在利妥昔单抗耐药细胞系（RRCL）和B细胞非霍奇金淋巴瘤（B-NHL）中的调节
6. Circulating Tfh1 (cTfh1) cell numbers and PD1 expression are elevated in low-grade B-cell non-Hodgkin’s lymphoma and cTfh gene expression is perturbed in marginal zone lymphoma [O] . Elliot T. Byford, Matthew Carr, Eleni Ladikou, -1

机译：在低度B细胞非霍奇金淋巴瘤中循环Tfh1（cTfh1）细胞数量和PD1表达升高而在边缘区淋巴瘤中cTfh基因表达受到干扰
7. Prognostic Value of miRNA-155 Expression in B-Cell Non-Hodgkin Lymphoma [O] . Ahmed M. L. Bedewy, Shereen M. Elmaghraby, Ahmed A. Shehata, 2017

机译：miRNa-155在B细胞非霍奇金淋巴瘤中表达的预后价值

Prognostic Value of miRNA-155 Expression in B-Cell Non-Hodgkin Lymphoma

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