Fluid strategies and outcomes in patients with acute respiratory distress syndrome systemic inflammatory response syndrome and sepsis: a protocol for a systematic review and meta-analysis

摘要

BackgroundFluid administration to critically ill patients remains the subject of considerable controversy. While intravenous fluid given for resuscitation may be life-saving, a positive fluid balance over time is associated with worse outcomes in critical illness. The aim of this systematic review is to summarise the existing evidence regarding the relationship between fluid administration or balance and clinically important patient outcomes in critical illness.