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An Evil Backstage Manipulator: Psychological Factors Correlated with Health-Related Quality of Life in Chinese Patients with Crohns Disease

机译:邪恶的后台操纵器:与克罗恩病患者健康相关的生活质量相关的心理因素

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摘要

Health-related quality of life (HRQoL) is recommended as one of essential parameters to evaluate treatment effect and clinical outcome in patients with Crohn's disease (CD). Recent studies reported that psychological factors might play a role in HRQoL in Western and American CD patients. Sufficient evidences in Chinese CD patients are still unavailable. This study is dedicated to investigate the correlation of various psychological factors with HRQoL in Chinese CD patients. We prospectively collected 40 active and 40 quiescent CD patients in China and found that psychological factors, especially neuroticism and anxiety, significantly correlate with and affect HRQoL in both active and quiescent CD groups. This is the first report revealing correlation between psychological factors and HRQoL in Chinese CD patients. Therefore, we assume that our results can contribute to a better understanding of etiology and tailoring of management in Chinese patients with Crohn's disease and are beneficial to our colleagues to compare the heterogeneous characteristics of Crohn's disease in different ethnic groups.
机译:建议将与健康相关的生活质量(HRQoL)作为评估克罗恩病(CD)患者的治疗效果和临床结果的必要参数之一。最近的研究报道,心理因素可能在西方和美国CD患者的HRQoL中起作用。中国CD患者尚无足够证据。本研究致力于探讨中国CD患者各种心理因素与HRQoL的相关性。我们前瞻性地收集了中国的40名活跃的CD患者和40名静态CD的患者,发现心理因素,尤其是神经质和焦虑,与活跃和静态CD组的HRQoL显着相关并对其产生影响。这是第一份揭示中国CD患者心理因素与HRQoL之间相关性的报告。因此,我们认为我们的结果有助于更好地了解中国克罗恩病患者的病因和适应性治疗,并且有利于我们的同事比较不同种族克罗恩病的异质性。

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