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Eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) as a differential diagnosis of hypereosinophilic syndromes

机译:嗜酸性肉芽肿合并多血管炎(以前称为Churg-Strauss综合征)可作为嗜酸性粒细胞增多综合征的鉴别诊断

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摘要

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome, is a rare systemic disease situated between primary small vessel vasculitides associated with antineutrophil cytoplasmic antibodies (ANCAs) and hypereosinophilic syndromes (HES). Here, we present a case of EGPA in a 38-year-old male, with a previous diagnosis of asthma, who presented with fever, migratory lung infiltrates and systemic eosinophilia that was refractory to previous courses of antibiotics. This case highlights the importance of the primary care physician understanding the differential diagnosis of pulmonary eosinophilic syndromes.
机译:嗜酸性肉芽肿性多血管炎(EGPA),以前称为Churg-Strauss综合征,是一种罕见的全身性疾病,位于与抗中性粒细胞胞浆抗体(ANCAs)和高嗜酸性粒细胞综合征(HES)相关的主要小血管血管炎之间。在这里,我们介绍了一名38岁的男性EGPA病例,该男性先前已诊断出哮喘,伴发烧,迁徙性肺浸润和全身性嗜酸粒细胞增多,对以前的抗生素疗程无能为力。该病例凸显了初级保健医师了解肺嗜酸性粒细胞综合征的鉴别诊断的重要性。

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