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Antifungal activity of water-stable copper-containing metal-organic frameworks

机译:耐水稳定的含铜金属有机骨架的抗真菌活性

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摘要

Although metal-organic frameworks (MOFs) or porous coordination polymers have been widely studied, their antimicrobial activities have not yet been fully investigated. In this work, antifungal activity of copper-based benzene-tricarboxylate MOF (Cu-BTC MOF), which is water stable and industrially interesting, is investigated against Candida albicans, Aspergillus niger, Aspergillus oryzae and Fusarium oxysporum. The Cu-BTC MOF can effectively inhibit the growth rate of C. albicans and remarkably inhibit the spore growth of A. niger, A. oryzae and F. oxysporum. This finding shows the potential of using Cu-BTC MOF as a strong biocidal material against representative yeasts and moulds that are commonly found in the food and agricultural industries.
机译:尽管金属有机骨架(MOF)或多孔配位聚合物已得到广泛研究,但其抗菌活性尚未得到充分研究。在这项工作中,研究了水稳定且工业上令人关注的铜基三羧酸铜MOF(Cu-BTC MOF)对白色念珠菌,黑曲霉,米曲霉和尖孢镰刀菌的抗真菌活性。 Cu-BTC MOF可以有效抑制白色念珠菌的生长速度,并显着抑制黑曲霉,米曲霉和尖孢镰刀菌的孢子生长。这一发现表明,使用Cu-BTC MOF作为强力杀菌材料的潜力,可以抗击食品和农业中常见的代表性酵母菌和霉菌。

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