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Skin Sparing Mastectomy with Preservation of Nipple Areola Complex and Immediate Breast Reconstruction in Patients with Breast Cancer: A Single Centre Prospective Study

机译:保留乳头乳晕复合物和乳腺癌患者立即乳房重建的皮肤保留乳房切除术:单中心前瞻性研究

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摘要

Background. Skin and nipple areola sparing mastectomy (NASM) has recently gained popularity as the management of breast cancer. This study aims to evaluate the aesthetic outcome, patient satisfaction, and oncological safety of NASM. Methods. The study prospectively analyzes the results of NASM and immediate breast reconstruction in 34 women with breast cancer. The criteria for inclusion were core biopsy-proven, peripherally located breast cancer of any tumor size and with any “N” status, with documented negative intraoperative frozen section biopsy of retroareolar tissue, and distance from the nipple to tumor margin >2 cm on mammography. Results. The median age of the patients was 45 years. The majority had either stage II or stage III breast cancer. The median mammographic distance of tumor from nipple areola complex (NAC) was 3.8 cm. The overall operative morbidity was minimal. The NAC could be preserved in all the patients. There was no local recurrence of tumor at median follow-up of 28.5 months. The aesthetic outcomes were satisfactory. Conclusion. NASM and immediate breast reconstruction can be successfully achieved with minimal morbidity and very low risk of local recurrence in appropriately selected breast cancer patients, with acceptable aesthetic results and good patient satisfaction.
机译:背景。保留皮肤和乳头乳晕的乳房切除术(NASM)最近由于乳腺癌的治疗而受到欢迎。这项研究旨在评估NASM的美学效果,患者满意度和肿瘤学安全性。方法。这项研究前瞻性地分析了34例乳腺癌女性的NASM和立即乳房重建的结果。纳入标准为经核心活检证实,任何肿瘤大小,任何“ N”状态,位于外周的乳腺癌,并记录有乳晕后组织的术中冰冻切片活检阴性,并且在乳腺X线摄影中乳头到肿瘤边缘的距离> 2 cm 。结果。患者的中位年龄为45岁。大多数患有II期或III期乳腺癌。距乳头乳晕复合体(NAC)的乳腺X线摄影术中位距离为3.8 cm。总体手术发病率极低。 NAC可以保留在所有患者中。中位随访28.5个月,无局部肿瘤复发。美学效果令人满意。结论。在适当选择的乳腺癌患者中,NASM和即刻乳房重建可以成功地实现,以最低的发病率和极低的局部复发风险,获得可接受的美学效果和良好的患者满意度。

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