Evaluation of Safe and Effectiveness of an Injectable Solution Acid Deoxycholic Based for Reduction of Localized Adiposities

机译：基于减少局部脂肪的酸性脱氧胆酸注射液的安全性和有效性评估

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Background:The use of deoxycholic acid to reduce localized fat deposits is a procedure that has been in use for about 30 years. Its effectiveness as treatment is due to emulsification of phospholipids and therefore, solubilization of the biological membranes with resulting fat necrosis. The purpose of the study was to assess the effectiveness and the safety of an injectable solution containing sodium deoxycholtate 1.25% (DB125), used as intralipotherapy.

机译：背景：使用脱氧胆酸减少局部脂肪沉积是一种已经使用约30年的方法。其治疗的有效性归因于磷脂的乳化，因此生物膜的溶解导致脂肪坏死。这项研究的目的是评估含有1.25％脱氧胆酸钠（DB125）的可注射溶液作为脂质内治疗的有效性和安全性。

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期刊名称 Plastic and Reconstructive Surgery Global Open
作者
Roberto Amore; Domenico Amuso; Vincenza Leonardi; Francesco Leva; Andrea Carnovale Sibaud; Antonio Guida; Ezio Costa; Ferdinando Terranova; Vincenzo Amodeo; Konstantinos Gkritzalas;
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年(卷),期 2018(6),6
年度 2018
页码 e1794
总页数 5
原文格式 PDF
正文语种
中图分类外科学;
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1. Efficacy, patient-reported outcomes and safety profile of ATX-101 (deoxycholic acid), an injectable drug for the reduction of unwanted submental fat: results from a phase III, randomized, placebo-controlled study [J] . Ascher B., Hoffmann K., Walker P., Journal of the European Academy of Dermatology and Venereology: JEADV . 2014,第12期

机译：ATX-101（脱氧胆酸）的功效，患者报告的结局和安全性，这是一种用于减少不必要的脑膜下脂肪的可注射药物：一项来自III期，随机，安慰剂对照研究的结果
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6. Efficacy patient-reported outcomes and safety profile of ATX-101 (deoxycholic acid) an injectable drug for the reduction of unwanted submental fat: results from a phase III randomized placebo-controlled study [O] . B Ascher, K Hoffmann, P Walker, -1

机译：ATX-101（脱氧胆酸）的功效患者报告的结局和安全性这是一种用于减少不必要的脑膜下脂肪的注射药物：一项来自III期随机安慰剂对照研究的结果
7. Efficacy, patient-reported outcomes and safety profile of ATX-101 (deoxycholic acid), an injectable drug for the reduction of unwanted submental fat : results from a phase III, randomized, placebo-controlled study [O] . Ascher, Benjamin, Hoffmann, Klaus, Walker, Patricia, 2014

机译：ATX-101（脱氧胆酸）的疗效，患者报告的结局和安全性，这是一种用于减少不必要的mentalmental submental脂肪的注射药物：III期随机安慰剂对照研究的结果

Evaluation of Safe and Effectiveness of an Injectable Solution Acid Deoxycholic Based for Reduction of Localized Adiposities

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