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Understanding autism: insights from mind and brain.

机译:了解自闭症:来自思想和大脑的见解。

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摘要

Autism is a developmental disorder characterized by impaired social interaction and communication as well as repetitive behaviours and restricted interests. The consequences of this disorder for everyday life adaptation are extremely variable. The general public is now more aware of the high prevalence of this lifelong disorder, with ca. 0.6% of the population being affected. However, the signs and symptoms of autism are still puzzling. Since a biological basis of autism was accepted, approaches from developmental cognitive neuroscience have been applied to further our understanding of the autism spectrum. The study of the behavioural and underlying cognitive deficits in autism has advanced ahead of the study of the underlying brain abnormalities and of the putative genetic mechanisms. However, advances in these fields are expected as methodological difficulties are overcome. In this paper, recent developments in the field of autism are outlined. In particular, we review the findings of the three main neuro-cognitive theories of autism: theory-of-mind deficit, weak central coherence and executive dysfunction.
机译:自闭症是一种发展障碍,其特征是社交互动和沟通受损,行为重复和利益受到限制。这种疾病对日常生活适应的影响是非常可变的。现在,公众更加意识到这种终生疾病的高流行,大约有受影响人口的0.6%。但是,自闭症的体征和症状仍然令人困惑。自从自闭症的生物学基础被接受以来,来自发展性认知神经科学的方法已被用于进一步理解自闭症谱系。自闭症的行为和潜在认知缺陷的研究已经领先于潜在的脑部异常和假定的遗传机制的研究。但是,由于克服了方法上的困难,因此有望在这些领域取得进展。本文概述了自闭症领域的最新发展。特别是,我们回顾了自闭症的三种主要神经认知理论的发现:心智缺陷,弱中枢连贯性和执行功能障碍。

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