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Design of a Global Medical Database which is Searchable by Human Diagnostic Patterns

机译:可通过人类诊断模式搜索的全球医学数据库的设计

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摘要

We describe a global medical database which is designed for efficient evaluation. It allows language independent search for human diagnostic parameters. Core of the database is a fully automated electronic archive and distribution server for medical histories of real but anonymous patients which contain patterns of diagnosis, chosen treatment, and outcome. Every pattern is represented by a feature vector which is usually a sequence of numbers, and labeled by an unambiguous "pattern name" which identifies its meaning. Similarity search is always done only over patterns with the same pattern name, because these are directly comparable. Similarities of patterns are mapped to spatial similarities (small distances) of their feature vectors using an appropriate metric. This makes them searchable. Pattern names can be "owned" like today domain names. This facilitates unbureaucratic definition of patterns e.g. by manufacturers of diagnostic devices. Application: If there is a new patient with certain diagnostic patterns, it is possible to combine a part or all of them and to search in the database for completed histories of patients with similar patterns to find the best treatment. Confinement of the result by conventional language based search terms is possible, and immediate individual statistics or regression analyses can quantify probabilities of success in case of different treatment choices. Conclusions: Efficient searching with diagnostic patterns is technically feasible. Labeled feature vectors induce a systematic and expandable approach. The database also allows immediate calculation of individual up to date prediction models.
机译:我们描述了旨在有效评估的全球医学数据库。它允许语言无关的搜索人类诊断参数。数据库的核心是一个全自动的电子存档和分发服务器,用于存储真实但匿名患者的病历,其中包括诊断,选择的治疗方法和结果。每个模式都由通常为数字序列的特征向量表示,并由标识其含义的明确的“模式名称”标记。始终仅对具有相同模式名称的模式进行相似性搜索,因为它们是直接可比较的。使用适当的度量,将模式的相似性映射到其特征向量的空间相似性(小距离)。这使它们可搜索。模式名称可以像今天的域名一样“拥有”。这有助于对模式进行非官僚的定义,例如由诊断设备的制造商提供。应用:如果有新的患者具有某些诊断模式,则可以将它们的一部分或全部合并,并在数据库中搜索具有相似模式的患者的完整病史,以找到最佳治疗方法。通过基于常规语言的搜索词来限制结果是可能的,并且即时的个体统计或回归分析可以量化在不同治疗选择的情况下成功的可能性。结论:利用诊断模式进行有效搜索在技术上是可行的。标记的特征向量引发了系统且可扩展的方法。该数据库还允许立即计算各个最新的预测模型。

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