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Phase III randomized trial of preoperative concurrent chemoradiotherapy versus preoperative radiotherapy for patients with locally advanced head and neck squamous cell carcinoma

机译：局部晚期头颈部鳞状细胞癌患者术前同期放化疗与术前放疗三期随机试验

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摘要

PurposeTo determine the role of preoperative concurrent chemoradiotherapy in the treatment of locally advanced head and neck squamous cell carcinoma (HNSCC).

机译：目的确定术前同时放化疗在治疗局部晚期头颈部鳞状细胞癌（HNSCC）中的作用。

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期刊名称 Oncotarget
作者
Junlin Yi; Xiaodong Huang; Zhengang Xu; Shaoyan Liu; Xiaolei Wang; Xiaohui He; Dehong Luo; Jingwei Luo; Jianping Xiao; Shiping Zhang; Kai Wang; Yuan Qu; Yuan Tang; Weixin Liu; Guozhen Xu; Li Gao; Dian Wang;
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作者单位

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年(卷),期 2017(8),27
年度 2017
页码 44842–44850
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;细胞生物学;
关键词
head and neck squamous cell carcinoma preoperative radiotherapy concurrent chemoradiotherapy multimodality treatment organ function preservation;

机译：头颈部鳞状细胞癌;术前放疗;同步放化疗;多模式治疗;器官功能保存;

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专利

1. Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma of the head and neck [J] . Mamoru Tsukuda, Junichi Ishitoya, Hideki Matsuda, Cancer Chemotherapy and Pharmacology . 2010,第4期

机译：多西他赛，顺铂和5-氟尿嘧啶同时放化疗联合CCRT联合顺铂，5-氟尿嘧啶，甲氨蝶呤和亚叶酸的随机对照II期比较研究在局部晚期头颈部鳞状细胞癌患者中的应用
2. Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma of the head and neck. [J] . Tsukuda M, Ishitoya J, Matsuda H, Cancer chemotherapy and pharmacology. . 2010,第4期

机译：随机对照期同期对多西紫杉醇，顺铂和5氟尿嘧啶与顺铂，5-氟尿嘧啶，甲氨蝶呤和白草素患者的头部和颈部临床和颈部癌症的随机化学疗法对比研究。
3. Panitumumab plus radiotherapy versus chemoradiotherapy in patients with unresected, locally advanced squamous-cell carcinoma of the head and neck (CONCERT-2): a randomised, controlled, open-label phase 2 trial [J] . Giralt Jordi, Trigo Jose, Nuyts Sandra, The lancet oncology . 2015,第2期

机译：Panitumumab联合放疗与放化疗联合治疗未切除的局部晚期头颈部鳞状细胞癌（CONCERT-2）：一项随机，对照，开放标签的2期试验
4. CCND1 as a Predictive Biomarker of Neoadjuvant Chemotherapy in Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma [C] . Zhien Feng, Lizhen Wang, Bingshun Wang, Academic Committee Conference of Shanghai key lab of stomatology . 2011

机译：CCND1作为局部晚期头颈部鳞状细胞癌患者新辅助化疗的预测生物标志物
5. EGFRvIII Expression and Signaling in head and neck squamous cell carcinoma. [D] . Wheeler, Sarah E. 2012

机译：EGFRvIII在头颈部鳞状细胞癌中的表达和信号传导。
6. Induction chemotherapy with concurrent chemoradiotherapy versus concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of head and neck: a meta-analysis [O] . Lijuan Zhang, Nan Jiang, Yuexian Shi, -1

机译：同步放化疗与同步放化疗对局部晚期头颈部鳞状细胞癌的诱导化疗：荟萃分析
7. Concurrent cisplatin and dose escalation with intensity-modulated radiotherapy (IMRT) versus conventional radiotherapy for locally advanced head and neck squamous cell carcinomas (HNSCC): GORTEC 2004-01 randomized phase III trial [O] . Yungan Tao, Anne Auperin, Pierre Blanchard, 2020

机译：随着强度调节放疗（IMRT）对局部先进头和颈鳞状细胞癌（HTSCC）的常规放疗（HOREC 2004-01随机阶段III试验，并发顺铂和剂量升级与常规放射治疗

Phase III randomized trial of preoperative concurrent chemoradiotherapy versus preoperative radiotherapy for patients with locally advanced head and neck squamous cell carcinoma

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